Comparative and Veterinary Pharmacology

1. Front Matter

   Pages i-x

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2. Topics in Veterinary Pharmacology

   1. Front Matter

      Pages 1-1

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   2. Introduction

      • Fiona Cunningham, Jonathan Elliott, Peter Lees

      Pages 3-17

   3. Species Differences in Pharmacokinetics and Pharmacodynamics

      • Pierre-Louis Toutain, Aude Ferran, Alain Bousquet-Mélou

      Pages 19-48

   4. Comparative and Veterinary Pharmacogenomics

      • Carrie M. Mosher, Michael H. Court

      Pages 49-77

   5. Drug Delivery Systems in Domestic Animal Species

      • David J. Brayden, Emilie J. M. Oudot, Alan W. Baird

      Pages 79-112

   6. Population Medicine and Control of Epidemics

      • Hafid Benchaoui

      Pages 113-138

   7. Interspecies Allometric Scaling

      • Robert P. Hunter

      Pages 139-157

   8. Pain and Analgesia in Domestic Animals

      • Alex Livingston

      Pages 159-189

   9. New Technologies for Application to Veterinary Therapeutics

      • Jim E. Riviere

      Pages 191-210

3. The Interface of Veterinary Pharmacology and Man

   1. Front Matter

      Pages 212-212

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   2. Genetically Modified Animals and Pharmacological Research

      • Dominic J. Wells

      Pages 213-226

   3. Antimicrobial Drug Resistance

      • Marilyn Martinez, Peter Silley

      Pages 227-264

   4. Drug Residues

      • Philip T. Reeves

      Pages 265-290

   5. Veterinary Medicines and the Environment

      • Alistair B. A. Boxall

      Pages 291-314

   6. Veterinary Medicines and Competition Animals: The Question of Medication Versus Doping Control

      • Pierre-Louis Toutain

      Pages 315-339

4. Back Matter

   Pages 341-348

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The human–animal bond has evolved and diversi?ed down the ages. Dogs, cats and even horses, have long ful?lled the role of faithful companion and indeed, as exempli?ed by the introduction of seeing and hearing dogs, there may be a critical level of co-dependency between the species. In the twenty-?rst century, the animal types that are kept as pets in many parts of the world are extensive ranging from reptiles through rodents to ruminants and beyond. As would be predicted by the nature of the relationship, the approach to treatment of a companion animal is often closely aligned to that which would have been offered to their owner. However, an increasing awareness of welfare issues, such as the recognition that animals expe- ence pain and the proven bene?ts of disease prevention in intensive farming units, together with the growth in zoos and wildlife parks, has increased the likelihood of food producing and non-domesticated animals receiving medicinal products during their life-time. Although many of the individual drugs or classes of drugs administered to animals are the same as, or derived from, those given to man, the safe and effective use of drugs in animals often cannot be achieved by simply transposing knowledge of drug action on, or behaviour in, the body from one species to another. The impact of the anatomical, physiological and pathophysiological variability that spans the animal kingdom can often profoundly alter drug response.

• Comparative Pharmacology
• Veterinary Pharmacology
• drug
• drug delivery
• drug resistance
• kinetics
• medicine
• pain
• pharmacodynamics
• pharmacokinetics
• pharmacology
• research
• resistance
• treatment
• veterinary medicine
• antibacterial drug resistance

• Dept. Veterinary Basic Sciences, Royal Veterinary College, Hertfordshire, United Kingdom

  Fiona Cunningham, Jonathan Elliott, Peter Lees

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