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Advanced Fluorescence Reporters in Chemistry and Biology I

Fundamentals and Molecular Design

  • Book
  • © 2010

Overview

Editors:
  1. Alexander P. Demchenko

    1. , Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine

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  • A comprehensive review
  • Written by experts
  • Contains numerous color illustrations
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Series on Fluorescence (SS FLUOR, volume 8)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  3. Design of Organic Dyes

    1. Front Matter

      Pages 25-25
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    2. Optimized UV/Visible Fluorescent Markers

      • M. Sameiro T. Gonçalves
      Pages 27-64

    3. Long-Wavelength Probes and Labels Based on Cyanines and Squaraines

      • Leonid D. Patsenker, Anatoliy L. Tatarets, Ewald A. Terpetschnig
      Pages 65-104

    4. Two-Photon Absorption in Near-IR Conjugated Molecules: Design Strategy and Structure–Property Relations

      • Olga V. Przhonska, Scott Webster, Lazaro A. Padilha, Honghua Hu, Alexey D. Kachkovski, David J. Hagan et al.
      Pages 105-147

    5. Discovery of New Fluorescent Dyes: Targeted Synthesis or Combinatorial Approach?

      • Eunha Kim, Seung Bum Park
      Pages 149-186

  4. Organic Dyes with Response Function

    1. Front Matter

      Pages 187-187
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    2. Physical Principles Behind Spectroscopic Response of Organic Fluorophores to Intermolecular Interactions

      • Vladimir I. Tomin
      Pages 189-223

    3. Organic Dyes with Excited-State Transformations (Electron, Charge, and Proton Transfers)

      • Cheng-Chih Hsieh, Mei-Lin Ho, Pi-Tai Chou
      Pages 225-266

    4. Dyes with Segmental Mobility: Molecular Rotors

      • Mark A. Haidekker, Matthew Nipper, Adnan Mustafic, Darcy Lichlyter, Marianna Dakanali, Emmanuel A. Theodorakis
      Pages 267-308

    5. Electrochromism and Solvatochromism in Fluorescence Response of Organic Dyes: A Nanoscopic View

      • Patrik R. Callis
      Pages 309-330

    6. Electric Field Sensitive Dyes

      • Ronald J. Clarke
      Pages 331-344

  5. Fluorophores of Visible Fluorescent Proteins

    1. Front Matter

      Pages 345-345
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  6. Fluorophores of visible Fluorescent Proteins

    1. Photophysics and Spectroscopy of Fluorophores in the Green Fluorescent Protein Family

      • Fabienne Merola, Bernard Levy, Isabelle Demachy, Helene Pasquier
      Pages 347-383

  7. Back Matter

    Pages 385-389
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Keywords

About this book

Fluorescence reporter is the key element of any sensing or imaging technology. Its optimal choice and implementation is very important for increasing the sensitivity, precision, multiplexing power, and also the spectral, temporal, and spatial reso- tion in different methods of research and practical analysis. Therefore, design of ?uorescence reporters with advanced properties is one of the most important problems. In this volume, top experts in this ?eld provide advanced knowledge on the design and properties of ?uorescent dyes. Organic dyes were the ?rst ?uorescent materials used for analytical purposes, and we observe that they retain their leading positions against strong competition of new materials – conjugated polymers, semiconductor nanocrystals, and metal chelating complexes. Recently, molecular and cellular biology got a valuable tool of organic ?uorophores synt- sized by cell machinery and incorporated into green ?uorescent protein and its analogs. Demands of various ?uorescence techniques operating in spectral, anisotropy, and time domains require focused design of ?uorescence reporters well adapted to these techniques. Near-IR spectral range becomes more and more attractive for various applications, and new dyes emitting in this range are strongly requested. Two-photonic ?uorescence has become one of the major tools in bioimaging, and ?uorescence reporters well adapted to this technique are in urgent need. These problems cannot be solved without the knowledge of fundamental principles of dye design and of physical phenomena behind their ?uorescence response.

Editors and Affiliations

  • , Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine

    Alexander P. Demchenko

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