Overview
Part of the book series: Advances in Anatomy, Embryology and Cell Biology (ADVSANAT, volume 196)
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Table of contents (9 chapters)
Keywords
About this book
In this monograph the authors have emphasized a number of important concepts in mammalian kidney development. Emphasis has been put on methodology so that the reader can understand how certain results or conclusions were reached and what the optimal methods for reliable results to be obtained are. In addition, as well as descriptions of the morphology there is information on the genetic basis of the structural development. In addition much attention has been paid to how nephron number may be altered by changes in the environment of the developing kidney and to the consequences for the remaining nephron gene expression and kidney function when total nephron number is altered. The consequences for the health of the adult, upon the formation of an adult kidney with altered nephron number and (potentially) gene expression, can be quite serious. The epigenetic mechanisms by which such changes can occur are introduced as a very fertile field for future investigation.
Authors and Affiliations
Bibliographic Information
Book Title: Factors Influencing Mammalian Kidney Development: Implications for Health in Adult Life
Authors: Karen M. Moritz, Marelyn Wintour-Coghlan, M. Jane Black, John F. Bertram, Georgina Caruana
Series Title: Advances in Anatomy, Embryology and Cell Biology
DOI: https://doi.org/10.1007/978-3-540-77768-7
Publisher: Springer Berlin, Heidelberg
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2008
Softcover ISBN: 978-3-540-77767-0Published: 10 June 2008
eBook ISBN: 978-3-540-77768-7Published: 11 May 2008
Series ISSN: 0301-5556
Series E-ISSN: 2192-7065
Edition Number: 1
Number of Pages: IX, 79
Topics: Nephrology, Human Physiology, Human Genetics