Progestins and the Mammary Gland

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

• Breast Cancer
• Endocrinology
• Mammary Gland
• Pharmacology
• Progesterone Receptor
• Regulation
• tissue

From the reviews:

"This book examines different aspects of progestin biology in the mammary gland, discussing both basic science and clinically relevant topics. The chapters are based on an international symposium that took place in Berlin in 2007. … The authors are all experts in their respective fields. … This exciting collection of chapters on important areas in progestin biology would be most interesting for researchers (and potentially clinicians) … . A number of novel research findings are discussed, as well as their potential applications." (Ronald N Cohen, Doody’s Review Service, August, 2008)

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