Memories: Molecules and Circuits

1. Front Matter

   Pages I-XIII

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2. The Neuroanatomy and Neuropsychology of Declarative and Nondeclarative Memory

   • Peter J. Bayley, Larry R. Squire

   Pages 1-18

3. Dynamics of Hippocampal-Cortical Interactions During Memory Consolidation: Insights from Functional Brain Imaging

   • Bruno Bontempi, Thomas P. Durkin

   Pages 19-39

4. From Molecule to Memory System: Genetic Analyses in Drosophila

   • Guillaume Isabel, Daniel Comas, Thomas Preat

   Pages 41-57

5. Towards a Molecular and Cellular Understanding of Remote Memory

   • Brian J. Wiltgen, Robert A. M. Brown, Lynn E. Talton, Alcino J. Silva

   Pages 59-67

6. Post-Activation State: A Critical Rite of Passage of Memories

   • Yadin Dudai

   Pages 69-82

7. Reactivation-Dependent Amnesia: Disrupting Memory Reconsolidation as a Novel Approach for the Treatment of Maladaptive Memory Disorders

   • Jonathan L. C. Lee, Barry J. Everitt

   Pages 83-98

8. The Organizing Principles of Real-Time Memory Encoding: Neural Clique Assemblies and Universal Neural Codes

   • Joe Z. Tsien

   Pages 99-112

9. Making and Retaining New Memories: The Role of the Hippocampus in Associative Learning and Memory

   • Wendy A. Suzuki

   Pages 113-124

10. Entorhinal Grid Cells and the Representation of Space

    • Francesca Sargolini, Edvard I. Moser

    Pages 125-135

11. The Prefrontal Cortex: Categories, Concepts, and Cognitive Control

    • Earl K. Miller

    Pages 137-154

12. Molecules that Disrupt Memory Circuits in Alzheimer’s Disease: The Attack on Synapses by Aβ Oligomers (ADDLs)

    • William L. Klein, Pascale N. Lacor, Fernanda G. De Felice, Sergio T. Ferreira

    Pages 155-179

13. Back Matter

    Pages 181-182

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Memory can be typically de?ned as the brain function enabling the encoding, storage and retrieval of sensory information. In operational terms, this de?nition implies that our central nervous system not only processes various sensory modalities, be they visual, tactile, auditory, olfactory or gustatory, but is also capable of forming, organizing and conserving memory traces for extended periods of time. At both psychological and physiological levels, there is now a consensus that memory must no longer be seen as a unitary phenomenon but rather as an ensemble of dynamic processes, each one being subserved by different brain regions organized into multiple memory systems that support different forms of memory and that constantly interact to ensure optimal performance during any given cognitive challenge. Despite remarkable progress achieved over the last 30 years in our understanding of the neural bases of cognitive processes and associated pathologies, the questions of how, where and when memory traces are formed in the brain remain central issues and continue to fuel much debate in the ?eld of cognitive neuroscience.

• Alzheimer
• anatomy
• associative learning
• brain imaging
• cognition
• cognitive control
• cortex
• memory
• memory disorder
• memory encoding
• memory reconsolidation
• neuroanatomy
• neurobiology
• neuropsychology
• psychology

• Laboratoire de Neurosciences Cognitives CNRS UMR 5106, Université de Bordeaux 1, Talence, France

  Bruno Bontempi

• Departments of Neurobiology Psychiatry and Biobehavioral Sciences Psychology and Brain Research Institute, UCLA, Los Angeles, USA

  Alcino J. Silva

• Pour la Recherche Thérapeutique, Fondation IPSEN, Paris Cedex 16, France

  Yves Christen

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