Vogel and Motulsky's Human Genetics

The fourth, completely revised edition of this classic reference and textbook presents a cohesive and up-to-date exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. In the 10 years since the appearance of the third edition, many new insights have emerged for understanding the genetic basis of development and function in human health and disease. Human genetics, with its emphasis on molecular concepts and techniques, has become a key discipline in medicine and the biomedical sciences.

The fourth edition has been extensively expanded by new chapters on timely topics such as epigenetics, pharmacogenetics, gene therapy, cloning, and genetic epidemiology, and databases for basic and clinical genetics. In addition a multi/chapter section giving an overview on the main model organisms (mouse, dog, worm, fly, fish) used in human genetics research has been introduced.

This book will be of interest to human and medical geneticists, scientists in all biomedical sciences, physicians and epidemiologists, as well as to graduate and postgraduate students who desire to learn the fundamentals of this fascinating field.

• Chromosom
• Mutation
• cancer
• chromosome
• development
• epidemiology
• epigenetics
• evolution
• gene therapy
• genes
• genetic epidemiology
• genetics
• genomics
• health
• human evolution

"...should be essential reading for all geneticists. Reading the contents alone sparked a sense of anticipation that made this book essential bedtime reading! ... -there's nothing boring here." Heredity
"...a classic textbook and compendium of information. It is, therefore, a distinct pleasure to open the third edition..." Trends in Genetics

From the reviews of the fourth edition:

“A series of high level reviews, produced with the help of 76 co-authors. … There is a welcome emphasis on formal genetics, which sets this book apart from most others. … This is a handsome book, printed on good quality paper, well bound, and generally produced to Springer’s customary high standard. … It will presumably mainly end up in libraries … . Anybody needing to prepare a lecture on one of the topics covered would be very glad to find a copy there.”­­­ (Andrew Read, Human Genetics, Vol. 128, 2010)

• Institute of Human Genetics, Medical University of Graz, Graz, Austria

  Michael R. Speicher

• Departments of Medicine (Division of Medical Genetics) and Genome Sciences, University of Washington School of Medicine, Seattle, USA

  Arno G. Motulsky

• Department of Genetic Medicine and Development, University of Geneva Medical School and University Hospitals of Geneva, Geneva, Switzerland

  Stylianos E. Antonarakis

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