Advanced Time-Correlated Single Photon Counting Techniques

1. Front Matter

   Pages I-XIX

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2. Optical Signal Recording

   Pages 1-9

3. Overview of Photon Counting Techniques

   Pages 11-25

4. Multidimensional TCSPC Techniques

   Pages 27-46

5. Building Blocks of Advanced TCSPC Devices

   Pages 47-60

6. Application of Modern TCSPC Techniques

   Pages 61-212

7. Detectors for Photon Counting

   Pages 213-261

8. Practice of TCSPC Experiments

   Pages 263-346

9. Final Remarks

   Pages 347-349

10. References

    Pages 351-387

11. Back Matter

    Pages 351-401

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In 1984 Desmond O’Connor and David Phillips published their comprehensive book „Time-correlated Single Photon Counting“. At that time time-correlated s- gle photon counting, or TCSPC, was used primarily to record fluorescence decay functions of dye solutions in cuvettes. From the beginning, TCSPC was an am- ingly sensitive and accurate technique with excellent time-resolution. However, acquisition times were relatively slow due to the low repetition rate of the light sources and the limited speed of the electronics of the 70s and early 80s. Moreover, TCSPC was intrinsically one-dimensional, i.e. limited to the recording of the wa- form of a periodic light signal. Even with these limitations, it was a wonderful te- nique. More than 20 years have elapsed, and electronics and laser techniques have made impressive progress. The number of transistors on a single chip has approximately doubled every 18 months, resulting in a more than 1,000-fold increase in compl- ity and speed. The repetition rate and power of pulsed light sources have increased by about the same factor.

• Diffuse optical tomography
• Fluorescence lifetime imaging
• Fluorescence lifetime spectroscopy
• Single molecule spectroscopy
• Time-correlated single photon counting
• fluorescence spectroscopy
• microscopy
• spectroscopy

• Department of Chemistry, The Pennsylvania State University, University Park, USA

  A. W. Castleman

• Max-Planck-Institut für Strömungsforschung, Göttingen, Germany

  J.P. Toennies

• Institut für Medizinische Optik, Universität München, München, Germany

  W. Zinth

• Becker & Hickl GmbH, Berlin, Germany

  Wolfgang Becker

Wolfgang Becker is a specialist of optical short-time measurement techniques and obtained his PhD 1979 in Berlin, Germany. Since 1993 he is the head of Becker & Hickl GmbH in Berlin. His field of interest is development and application of time-correlated single photon counting techniques. He is an amatuer astronomer and telescope maker and likes cats, skiing and beach volleyball.

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