Overview
- Provides an update on current treatment and recent trials concerning progressive multiple sclerosis (MS)
- Guides physicians who manage patients with progressive MS
- Reviews current theories concerning pathophysiological mechanisms of progressive MS disease progression
- Relates basic research to potential therapies in progressive MS
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This revised, updated second edition draws together the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease. New additions to the second edition include a description of clinical scales used to determine levels of disability; recent trials specifically directed at reducing disease progression; rehabilitation; and an in depth discussion of the similarities and differences between primary and secondary multiple sclerosis.
The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which have been and will be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail.
Progressive Multiple Sclerosis, Second Edition is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease.
Reviews
Editors and Affiliations
About the editor
Dr Alastair Wilkins (BA, MB,BChir, PhD(Cantab)) is Reader in Neurology, University of Bristol, and Consultant Neurologist at Southmead Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
Bibliographic Information
Book Title: Progressive Multiple Sclerosis
Editors: Alastair Wilkins
DOI: https://doi.org/10.1007/978-3-319-65921-3
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing AG 2018
Hardcover ISBN: 978-3-319-65920-6Published: 13 December 2017
Softcover ISBN: 978-3-319-88132-4Published: 05 September 2018
eBook ISBN: 978-3-319-65921-3Published: 24 November 2017
Edition Number: 2
Number of Pages: IX, 307
Number of Illustrations: 15 b/w illustrations, 6 illustrations in colour
Topics: Neurology, Internal Medicine, General Practice / Family Medicine