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Chikungunya Virus

Advances in Biology, Pathogenesis, and Treatment

  • Book
  • © 2016

Overview

Editors:
  1. Chioma M. Okeoma

    1. Department of Microbiology, University of Iowa, Iowa City, USA

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  • Details the epidemiological outlook and clinical syndrome of CHIKV

  • Numerous graphs and charts illustrate key points

  • Contributions made by experts of CHIKV

  • Includes supplementary material: sn.pub/extras

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  2. Clinical Syndrome and Therapy

    • Sylvie Abel, André Cabié
    Pages 1-17

  3. Host Response and Mechanisms of Subversion of Chikungunya

    • Lisa F. P. Ng, Pierre Roques
    Pages 19-32

  4. Epidemiological History of Chikungunya Virus

    • Ann M. Powers
    Pages 33-44

  5. Vaccines Against Chikungunya Virus Infection

    • Karl Ljungberg, Beate M. Kümmerer, Pierre Roques, Mariano Esteban, Andres Merits, Peter Liljeström
    Pages 45-62

  6. Function of Chikungunya Virus Structural Proteins

    • Stefan W. Metz, Gorben P. Pijlman
    Pages 63-74

  7. Functions of Chikungunya Virus Nonstructural Proteins

    • Tero Ahola, Andres Merits
    Pages 75-98

  8. Interaction of Chikungunya Virus with the Mosquito Vector

    • Konstantin Tsetsarkin, Lark L. Coffey, Scott C. Weaver
    Pages 99-126

  9. Chikungunya Virus Entry and Replication

    • Nathalie Chazal, Laurence Briant
    Pages 127-148

  10. Chikungunya Virus-Induced Autophagy and Apoptosis

    • Delphine Judith, Thérèse Couderc, Marc Lecuit
    Pages 149-159

  11. Chikungunya Virus Pathogenesis

    • David W. Hawman, Thomas E. Morrison
    Pages 161-183

  12. Restriction Factors and Chikungunya Virus

    • Wadie D. Mahauad-Fernandez, Chioma M. Okeoma
    Pages 185-197
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Keywords

About this book

This book describes the molecular biology, pathogenesis, epidemiology, and potential strategies for control of chikungunya virus (CHIKV) infection. It offers insight into the structure and functions of CHIKV proteins as they relate to host response, interaction with the arthropod vector, and vaccination. A detailed account of both the epidemiological outlook and the clinical syndrome of CHIKV infection is provided. The complex host-virus interaction and the signaling pathways that mediate such interactions are also covered. Throughout the book, graphics and charts are used to provide stimulating discussion on important findings in the field of chikungunyalogy. The chapters are written with a global perspective by experts of CHIKV from around the world. This project is especially significant given that CHIKV is a pathogen of worldwide public health concern. Although the presence of CHIKV infection is not global yet, worldwide dissemination is predicted in the future due largely to the lack of effective treatment/therapy, efficient control of transmission, and knowledge about mechanisms of pathogenesis. Additionally, globalization of CHIKV is predicated on its mode of dissemination (mosquito vector) and cross border travel and migration.

Editors and Affiliations

  • Department of Microbiology, University of Iowa, Iowa City, USA

    Chioma M. Okeoma

About the editor

Chioma M. Okeoma, Ph.D

Department of Microbiology

Carver College of Medicine

University of Iowa

Bibliographic Information

  • Book Title: Chikungunya Virus

  • Book Subtitle: Advances in Biology, Pathogenesis, and Treatment

  • Editors: Chioma M. Okeoma

  • DOI: https://doi.org/10.1007/978-3-319-42958-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • License: CC BY

  • Hardcover ISBN: 978-3-319-42956-4Published: 16 December 2016

  • Softcover ISBN: 978-3-319-82704-9Published: 30 April 2018

  • eBook ISBN: 978-3-319-42958-8Published: 01 December 2016

  • Edition Number: 1

  • Number of Pages: X, 197

  • Number of Illustrations: 8 b/w illustrations, 31 illustrations in colour

  • Topics: Virology, Epidemiology, Vaccine

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