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Host Defense Peptides and Their Potential as Therapeutic Agents

  • Book
  • © 2016

Overview

  • Summarizes the latest developments in host defense peptides research
  • Explores potential therapeutic applications of host defense peptides
  • Written by international experts of host defense peptide research
  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. Biological Targets of Host Defense Peptides

  2. Immune Modulation by Host Defense Peptides

  3. Development of Resistance

  4. Recent Advances in Engineering Host Defense Peptides

  5. Therapeutic Perspectives

Keywords

About this book

This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory properties, and review recent advances in the design of novel therapeutic molecules. Lastly, their potential to prevent preterm births and Staphylococcus aureus infections is highlighted. The book is of interest to researchers, industry and clinicians alike.

Editors and Affiliations

  • Health Sciences Centre, McMaster University, Hamilton, Canada

    Richard M. Epand

About the editor

RICHARD M. EPAND Professor Emeritus McMaster University Dept. of Biochemistry and Biomedical Sciences 4H28 Health Sciences Centre Hamilton, Ontario Canada L8S 4K1 Tel. 905-525-9140 ext. 22073 Email: epand@mcmaster.ca 450 publications

Bibliographic Information

  • Book Title: Host Defense Peptides and Their Potential as Therapeutic Agents

  • Editors: Richard M. Epand

  • DOI: https://doi.org/10.1007/978-3-319-32949-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-32947-5Published: 16 May 2016

  • Softcover ISBN: 978-3-319-81406-3Published: 27 May 2018

  • eBook ISBN: 978-3-319-32949-9Published: 06 May 2016

  • Edition Number: 1

  • Number of Pages: X, 321

  • Number of Illustrations: 9 b/w illustrations, 32 illustrations in colour

  • Topics: Protein Science, Immunology, Applied Microbiology, Medical Biochemistry, Microbiology

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