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Endocannabinoids

  • Book
  • © 2015

Overview

Editors:
  1. Roger G. Pertwee

    1. Professor of Neuropharmacology, University of Aberdeen Institute of Medical Sciences, Aberdeen, United Kingdom

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  • Enriches understanding of the physiology, pathophysiology and pharmacology of the endocannabinoid system
  • Illustrates potential treatment strategies
  • Written by leading experts in the field

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 231)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xii
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  2. Endocannabinoids and Their Pharmacological Actions

    • Roger G. Pertwee
    Pages 1-37

  3. Biosynthesis and Fate of Endocannabinoids

    • Maria Grazia Cascio, Pietro Marini
    Pages 39-58

  4. Distribution of the Endocannabinoid System in the Central Nervous System

    • Sherry Shu-Jung Hu, Ken Mackie
    Pages 59-93

  5. The Potential of Inhibitors of Endocannabinoid Metabolism for Drug Development: A Critical Review

    • Christopher J. Fowler
    Pages 95-128

  6. Genetic Manipulation of the Endocannabinoid System

    • Andreas Zimmer
    Pages 129-183

  7. Endocannabinoids and the Immune System in Health and Disease

    • Guy A. Cabral, Gabriela A. Ferreira, Melissa J. Jamerson
    Pages 185-211

  8. Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis

    • Gareth Pryce, David Baker
    Pages 213-231

  9. Endocannabinoids and Neurodegenerative Disorders: Parkinson’s Disease, Huntington’s Chorea, Alzheimer’s Disease, and Others

    • Javier Fernández-Ruiz, Julián Romero, José A. Ramos
    Pages 233-259

  10. Endocannabinoids and Mental Disorders

    • TIziana Rubino, Erica Zamberletti, Daniela Parolaro
    Pages 261-283

  11. Cannabis and Endocannabinoid Signaling in Epilepsy

    • István Katona
    Pages 285-316

  12. Endocannabinoids and the Endocrine System in Health and Disease

    • Cecilia J. Hillard
    Pages 317-339

  13. Endocannabinoids and Reproductive Events in Health and Disease

    • Natalia Battista, Monica Bari, Mauro Maccarrone
    Pages 341-365

  14. Endocannabinoids and Metabolic Disorders

    • Blandine Gatta-Cherifi, Daniela Cota
    Pages 367-391

  15. Endocannabinoids and the Cardiovascular System in Health and Disease

    • Saoirse Elizabeth O’Sullivan
    Pages 393-422

  16. Endocannabinoids and the Digestive Tract and Bladder in Health and Disease

    • Angelo A. Izzo, Giulio G. Muccioli, Michael R. Ruggieri, Rudolf Schicho
    Pages 423-447

  17. Endocannabinoids and Cancer

    • Guillermo Velasco, Cristina Sánchez, Manuel Guzmán
    Pages 449-472

  18. Back Matter

    Pages 473-475
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Keywords

About this book

There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoid system and potential strategies for targeting this system in the clinic.

Editors and Affiliations

  • Professor of Neuropharmacology, University of Aberdeen Institute of Medical Sciences, Aberdeen, United Kingdom

    Roger G. Pertwee

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