Optimizing Treatment for Children in the Developing World

This book is intended to communicate current best practice in pediatric clinical pharmacology and clinical pharmacy with special consideration of the prevailing circumstances and most pressing needs in developing countries. It also addresses measures that may be taken in countries with emerging economies through organizational and political adjustments to reduce unacceptable levels of morbidity and mortality among children and pregnant women with treatable diseases.

• Access to treatment for children at every age
• Affordability of medicines
• Development of drugs for children
• Pediatric pharmacology
• Political initiatives
• Provision of healthcare
• pharmacotherapy

• Department of Pediatrics, University of British Columbia, Vancouver, Canada

  Stuart MacLeod

• University of Melbourne Medical School, Melbourne, VIC, Australia

  Suzanne Hill

• Departments of Pediatrics and Pharmacology, University of Toronto, Toronto, Canada

  Gideon Koren

• Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska University, Hostpital Karolinska Institutet, Stockholm, Sweden

  Anders Rane

Since 2003, Dr Stuart MacLeod has been Professor of Pediatrics at the University of British Columbia in Vancouver, Canada. He was also Director of the Child & Family Research Institute at BC Children’s Hospital until January 2010 and remains a senior clinician scientist at the Institute.

Dr MacLeod received an MD from the University of Toronto in 1967 and completed postgraduate training in clinical pharmacology in 1973 at McGill University where he obtained a PhD in pharmacology in 1972. In the early stages of his career his research interests focused on biochemical pharmacology, drug hepatotoxicity and drug biotransformation. In 1979 Dr MacLeod became the founding leader of a Division of Pediatric Clinical Pharmacology at Toronto’s Hospital for Sick Children. This University of Toronto unit has now thrived for 35 years and is the world’s leading centre for training and research in pediatric pharmacology and toxicology.

Dr MacLeod served as Dean of the Faculty of Health Sciences at McMaster University (1987-1992) and following the deanship founded the Centre for Evaluation of Medicines with a focus on therapeutics teaching, clinical pharmacology, population health sciences and pharmacoepidemiology.

Since 1986, Dr MacLeod has held a major interest in international health with a focus on African maternal-child health. His current scientific interests embrace the multitude of factors that influence safe and effective drug treatments for children and the use of research findings to inform clinical and public policy.

Policies and ethics