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The NeuroMuscular System: From Earth to Space Life Science

Neuromuscular Cell Signalling in Disuse and Exercise

  • Book
  • © 2015

Overview

Authors:
  1. Dieter Blottner

    1. Vegetative Anatomy, Charité Universitätsmedizin Berlin, Berlin, Germany

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  2. Michele Salanova

    1. Vegetative Anatomy, Charité Universitätsmedizin Berlin, Berlin, Germany

    View author publications

    You can also search for this author in PubMed   Google Scholar

  • Provides an overview on structure and function of the NeuroMuscular system
  • Discusses in detail the mechanisms of subcellular communication over neuromuscular junctions
  • Methods to counteract loss of neuromuscular activity in space and during the ageing process are discussed
  • Includes supplementary material: sn.pub/extras

Part of the book series: SpringerBriefs in Space Life Sciences (BRIEFSSLS, volume 0)

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Table of contents (4 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. General Introduction

    • Dieter Blottner, Michele Salanova
    Pages 1-7

  3. Skeletal Muscle

    • Dieter Blottner, Michele Salanova
    Pages 9-62

  4. Neuromuscular System

    • Dieter Blottner, Michele Salanova
    Pages 63-87

  5. Physical Countermeasure in Space: Efforts in Vain?

    • Dieter Blottner, Michele Salanova
    Pages 89-92
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Keywords

About this book

The book provides fundamental new insights in the structure and function of the healthy  NeuroMuscular system. Recent findings suggest that the musculoskeletal system that supports movement control on Earth is controlled by unique principles of structural, biochemical and molecular characteristics. Mechanical loading by working against normal gravity helps to support principal structures in bone, muscle and associated subcellular scaffold components. Disuse or immobilization of the body in bed rest on Earth or in microgravity in Space result in considerable loss of bone, muscle and force with downregulation of neuromuscular activity resulting in impaired performance control. The goal is to develop exercise prescriptions to maintain postural control in normal life, aging and rehabilitation on Earth as well as for an adequate human performance management in Space.

Authors and Affiliations

  • Vegetative Anatomy, Charité Universitätsmedizin Berlin, Berlin, Germany

    Dieter Blottner, Michele Salanova

About the authors

Prof. Dr. rer. nat. Dieter Blottner is Professor in Anatomy at the Charité Universitätsmedizin Berlin, Campus Charité Mitte (CCM), CC02, Vegetative Anatomy, and Head of the Research Group “Neuromuscular System” at the Berlin Center of Space Medicine (ZWMB, www.charite-in-space.de), Charité - Universitätsmedizin Berlin, Berlin, Germany. dieter.blottner@charite.de




Dr. Michele Salanova (Ph.D.) is Associate Research Scientist in the Group “Neuromuscular System” at the Berlin Center of Space Medicine (ZWMB, , www.charite-in-space.de), Vegetative Anatomy (CCO2), Charité - Universitätsmedizin, Berlin, Germany. Is principal investigator (PI) and co-principal investigator (CO-PI) of several NASA and ESA selected projects. michele.salanova@charite.de


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