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Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology

Scientific and Clinical Aspects of Anemia in Cancer

  • Book
  • © 2008

Overview

Editors:
  1. Mohammad Resa Nowrousian

    1. Department of Internal Medicine (Cancer Research), West German Cancer Center, University Hospital of Essen, Essen, Germany

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  • Comprehensive presentation of anemia in cancer and its treatment
  • Assessment of current and potential applications of erythropoietin
  • Presented by world experts in the field
  • Includes supplementary material: sn.pub/extras

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Physiology of erythropoiesis

    • Ugo Testa
    Pages 1-66

  3. Biology of EPO and EPO-receptor

    • Catherine Lacombe, P. Mayeux
    Pages 67-80

  4. The role of erythropoietin receptor expression on tumor cells

    • Joachim Fandrey
    Pages 81-102

  5. Problems associated with erythropoietin receptor determination on tumor cells

    • Anders Österborg
    Pages 103-115

  6. Definition, classification and characterization of anemia in cancer

    • M. R. Nowrousian
    Pages 117-148

  7. Pathophysiology of anemia in cancer

    • M. R. Nowrousian
    Pages 149-188

  8. Prevalence and incidence of anemia and risk factors for anemia in patients with cancer

    • Heinz Ludwig
    Pages 189-206

  9. Significance of anemia in cancer chemotherapy

    • M. R. Nowrousian
    Pages 207-248

  10. Incidence and impact of anemia in radiation oncology

    • Jürgen Dunst, M. Molls
    Pages 249-263

  11. Relationship between hemoglobin levels and tumor oxygenation

    • Peter Vaupel, Arnulf Mayer, Michael Höckel
    Pages 265-282

  12. Tumor hypoxia and therapeutic resistance

    • Peter Vaupel, Michael Höckel
    Pages 283-305

  13. Symptoms of anemia

    • Robert Pirker
    Pages 307-315

  14. Impact of anemia and red blood cell transfusion on organ function

    • M. R. Nowrousian
    Pages 317-367

  15. Relationship of hemoglobin, fatigue, and quality of life in anemic cancer patients

    • Zeeshan Butt, David Cella
    Pages 369-391

  16. When to use red blood cell transfusions in cancer patients with solid tumours?

    • Jayin K. Jacob, Peter J. Barrett-Lee
    Pages 393-405

  17. Pharmacology, pharmacokinetics and safety of recombinant human erythropoietin preparations

    • Wolfgang Jelkmann
    Pages 407-431

  18. Epoetin treatment of anemia associated with multiple myeloma and non-Hodgkin’s lymphoma

    • Anders Österborg
    Pages 433-448

  19. rhEPO in anemic patients with solid tumors and chemotherapy — efficacy and safety

    • M. R. Nowrousian
    Pages 449-508

  20. Early intervention with recombinant human erythropoietin for chemotherapy-induced anemia

    • Gary H. Lyman, John Glaspy
    Pages 509-530
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Keywords

About this book

Anemia is a frequent complication of cancer and its treatment. It produces many symptoms and significantly impairs metabolic and physiologic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. This book, now being published in its second edition, comprehensively presents the current knowledge on anemia in cancer and its treatment with rhEPO. Future developments are also discussed. Based on updated and new chapters, including a broader spectrum of topics, outstanding international experts describe the scientific and clinical aspects of anemia in various fields of oncology and give diagnostic and therapeutic recommendations on when and how to use rhEPO. The book, considered as a standard work, will again serve as an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.

Editors and Affiliations

  • Department of Internal Medicine (Cancer Research), West German Cancer Center, University Hospital of Essen, Essen, Germany

    Mohammad Resa Nowrousian

Bibliographic Information

  • Book Title: Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology

  • Book Subtitle: Scientific and Clinical Aspects of Anemia in Cancer

  • Editors: Mohammad Resa Nowrousian

  • DOI: https://doi.org/10.1007/978-3-211-69459-6

  • Publisher: Springer Vienna

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Vienna 2008

  • Hardcover ISBN: 978-3-211-25223-9Published: 19 December 2007

  • Softcover ISBN: 978-3-7091-1904-4Published: 23 August 2016

  • eBook ISBN: 978-3-211-69459-6Published: 14 June 2010

  • Edition Number: 2

  • Number of Pages: XVIII, 866

  • Topics: Oncology, Radiotherapy, Hematology, Surgery, Pharmacology/Toxicology, Blood Transfusion Medicine

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