Brain Edema XII

1. Front Matter

   Pages I-XV

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2. General review

   1. Front Matter

      Pages 1-1

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   2. Concept and pathogenesis of “hypoxic-ischemic encephalopathy”

      • Riki Okeda

      Pages 3-6

   3. Pathophysiology of traumatic brain edema: current concepts

      • Anthony Marmarou

      Pages 7-10

   4. Brain edema from intracerebral hemorrhage

      • Julian T. Hoff, G. Xi

      Pages 11-15

   5. Hydrostatic brain edema: basic mechanisms and clinical aspect

      • Katsuji Shima

      Pages 17-20

   6. Non-invasive imaging methods for the characterization of the pathophysiology of brain ischemia

      • Konstantin-A. Hossmann

      Pages 21-27

   7. Cécile & Oskar Vogt: The significance of their contributions in modern neuroscience

      • Igor Klatzo

      Pages 29-32

3. Imaging

   1. Front Matter

      Pages 33-33

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   2. Estimating blood-brain barrier opening in a rat model of hemorrhagic transformation with Patlak plots of Gd-DTPA contrast-enhanced MRI

      • Joseph D. Fenstermacher, R. A. Knight, J. R. Ewing, T. Nagaraja, V. Nagesh, J. S. Yee et al.

      Pages 35-37

   3. Recent development ofMR imaging technique for the investigation of brain function

      • Osamu Takizawa

      Pages 39-40

   4. Energy metabolism and cerebral blood flow during cytotoxic brain edema induced by 6-aminonicotinamide

      • Daisaku Kurita, M. Haida, Y. Shinohara

      Pages 41-44

   5. PET neuroreceptor imaging as predictor of severe cerebral ischemic insult

      • Tadashi Nariai, Y. Shimada, K. Ishiwata, T. Nagaoka, J. Shimada, T. Kuroiwa et al.

      Pages 45-48

   6. PET investigation of post-traumatic cerebral blood volume and blood flow

      • Naoya Hattori, S.-C. Huang, H.-M. Wu, W. Liao, T. C. Glenn, P. M. Vespa et al.

      Pages 49-52

   7. Quantitative evaluation of cerebral vascular permeability using multi-slice dynamic CT

      • Kyojiro Nambu, T. Nariai, T. Terada

      Pages 53-55

   8. Acetazolamide vasoreactivity evaluated by transcranial harmonic perfusion imaging: relationship with transcranial Doppler sonography and dynamic CT

      • Toshiyuki Shiogai, M. Koshimura, Y. Murata, H. Nomura, A. Doi, M. Makino et al.

      Pages 57-62

   9. Functional brain imaging of optical topography

      • Tsuneaki Kawaguchi

      Pages 63-64

4. Experimental global ischemia

   1. Front Matter

      Pages 65-65

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   2. Significant shrinkage of extracellular space during global cerebral ischemia: differences in gray and white matter ischemia

      • Eiji Kumura, C. Dohmen, R. Graf, T. Yoshimine, W.-D. Heiss

      Pages 67-70

   3. NTP and PCr responses to hypoxia by hypothermic and normothermic respiring, superfused, neonatal rat cerebrocortical slices: an NMR spectroscopy study at 14.1 Tesla

      • Lawrence Litt, K. Hirai, V. J. Basus, T. L. James

      Pages 71-74

Brain edema is a simple phenomenon – an abnormal increase of brain tissue volume by the increase of brain tissue water content. However the etiology is not simple and relating to a wide variety of neurological disorders including ischemia, trauma, tumor, hemorrhage and hydrocephalus. It is still a major cause of death in the neurological/neurosurgical ward. This volume is an up-to-date report on progress in brain edema research, diagnosis and treatment, including papers presented at the 12th International Symposium on Brain Edema and Brain Tissue Injury in 2002. Major topics include molecular biology and blood-brain barrier disorders, ischemic and traumatic brain edema, imaging and diagnosis of brain edema, treatment and radiation effect. Various papers in the rapidly growing fields of neuroimaging and molecular medicine are also included.

• Hydrocephalus
• blood brain barrier
• brain
• brain edema
• brain oedema
• cerebral metabolism
• ischemia
• spinal cord
• trauma
• tumor

• Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan

  T. Kuroiwa

• Institute für Chirurgische Forschung, Ludwig-Maximilians-Universität, München, Germany

  A. Baethmann

• Department of Neurosurgery, Polish Academy of Scienes, Warsaw, Poland

  Z. Czernicki

• Section of Neurosurgery, University of Michigan, Ann Arbor, USA

  J. T. Hoff

• Department of Neurosurgery, Musashino Red Cross Hospital, Tokyo, Japan

  U. Ito

• Department of Neurological Surgery, Nihon University, Tokyo, Japan

  Y. Katayama

• Medical College of Virgina, Richmond, USA

  A. Marmarou

• Department of Neurosurgery, Newcastle Gerneral Hospital, Newcastle-upon-Tyne, UK

  B. A. D. Mendelow

• Neurochirurgische Universitätklinik, Ludwig-Maximilians-Universität, München, Germany

  H.-J. Reulen

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