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Recombinant Protein Drugs

  • Book
  • © 2001

Overview

Editors:
  1. Peter Buckel

    1. Xantos Biomedicine, Martinsried, Germany

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Part of the book series: Milestones in Drug Therapy (MDT)

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Table of contents (8 chapters)

  1. Front Matter

    Pages I-X
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  2. Pioneers and business

    1. Front Matter

      Pages 1-1
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    2. Recombinant interferon - the 20th anniversary

      • Charles Weissmann
      Pages 3-41

    3. Combining science and business: from recombinant DNA to vaccines against hepatitis B virus

      • Peter Hans Hofschneider, Kenneth Murray
      Pages 43-64

  3. First generation proteins

    1. Front Matter

      Pages 65-65
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    2. Clotting factors VIII and IX

      • George G. Brownlee, Paul L. F. Giangrande
      Pages 67-88

    3. Colony-stimulating factors: altering the practice of oncology

      • Karl Welte, Erich Platzer
      Pages 89-106

    4. Tissue-type plasminogen activator: helping patients with acute myocardial infarction

      • Désiré Collen, H. Roger Lijnen
      Pages 107-126

  4. Proteins with new functions: protein engineering

    1. Front Matter

      Pages 127-127
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    2. Designing immunocytokines: genetically engineered fusion proteins for targeted immune therapy

      • Stephen D. Gillies
      Pages 129-147

  5. Further improvement of protein drugs

    1. Front Matter

      Pages 149-149
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    2. Improving protein therapeutics: the evolution of the modern pharmacopoeia

      • Paul A. Burke, Scott D. Putney
      Pages 151-168

    3. Principles of gene transfer and foreign protein expression for human gene therapy

      • Theodore Friedmann
      Pages 169-180

  6. Back Matter

    Pages 181-207
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Keywords

About this book

Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products. More than thirty different proteins are available for a variety of clinical applications, over 300 proteins are presently being evaluated in clinical trials. In this new volume of the MDT series, historical, technical and clinical aspects of recombinant protein drug discovery and development are presented, covering past, present and future highlights. Leading scientists and co-founders of early Biotech companies describe technical breakthroughs and the fascinating story of pioneering discoveries, as well as the long way of translating them into products and business. Therefore, this book represents an exciting documentation of the beginning of a new era in the pharmaceutical industry. In addition, scientists from basic research, clinic and industry actively involved in new developments discuss...

Editors and Affiliations

  • Xantos Biomedicine, Martinsried, Germany

    Peter Buckel

Bibliographic Information

  • Book Title: Recombinant Protein Drugs

  • Editors: Peter Buckel

  • Series Title: Milestones in Drug Therapy

  • DOI: https://doi.org/10.1007/978-3-0348-8346-7

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Verlag 2001

  • Hardcover ISBN: 978-3-7643-5904-1Published: 01 August 2001

  • Softcover ISBN: 978-3-0348-9527-9Published: 23 October 2012

  • eBook ISBN: 978-3-0348-8346-7Published: 06 December 2012

  • Series ISSN: 2296-6056

  • Series E-ISSN: 2296-6064

  • Edition Number: 1

  • Number of Pages: X, 207

  • Topics: Medicine/Public Health, general

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