Editors:
- Contains key readily reproducible experimental approaches certain to be useful as technologies continue to develop
- Details basic requirements for the most recent techniques still awaiting experimental substantiation
- Fosters rigorous scientific interactions among basic and clinical researchers aimed at further molecular demarcation of the elaborate pathways leading from inflammation to tumor formation
- Compiles contemporary laboratory techniques with an emphasis on carcinogenic events mediated by chronic inflammation and pathogen infection
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 511)
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Table of contents (16 protocols)
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Front Matter
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Experimental Approaches to Study Chronic Inflammation – Related Carcinogenesis
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Oncogenic Potential of Inflammation Induced by Viral and Bacterial Infections
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Back Matter
About this book
According to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 1, Experimental Models and Practical Approaches provides an overview of a spectrum of techniques developed to analyze the outcomes of inflammation-mediated carcinogenesis on the tissue, cellular, and molecular levels while highlighting several diagnostic aspects, such as biomarker discovery and molecular signatures evaluation. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
Editors and Affiliations
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National Cancer Institute at Frederick, SAIC-Frederick, Inc., Frederick, USA
Serguei V. Kozlov
Bibliographic Information
Book Title: Inflammation and Cancer
Book Subtitle: Methods and Protocols: Volume 1, Experimental Models and Practical Approaches
Editors: Serguei V. Kozlov
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-59745-447-6
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2009
Hardcover ISBN: 978-1-934115-14-5Published: 17 April 2009
Softcover ISBN: 978-1-61737-923-9Published: 19 November 2010
eBook ISBN: 978-1-59745-447-6Published: 05 April 2009
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 378
Number of Illustrations: 75 b/w illustrations
Topics: Cancer Research, Oncology, Laboratory Medicine