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  • © 2011

Epigenetic Aspects of Chronic Diseases

  • Cutting edge of current research – brings up-to-date information on how epigenetics contributes to a disease

  • Well illustrated with color images including cartoons to help understand complex mechanisms

  • Coverage of many diseases within one volume assists and stimulates cross-referencing between different diseases

  • Careful editing of each chapter ensures consistency and clarity of language

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xvii
  2. Epigenetics and Chronic Diseases: An Overview

    • Rebecca Smith, Jonathan Mill
    Pages 1-20
  3. Techniques to Study DNA Methylation and Histone Modification

    • Ester Lara, Vincenzo Calvanese, Agustin F. Fernandez, Mario F. Fraga
    Pages 21-39
  4. Mechanisms of Epigenetic Gene Silencing

    • Marie-Pierre Lambert, Zdenko Herceg
    Pages 41-53
  5. Autoimmune Diseases

    • Travis Hughes, Amr H. Sawalha
    Pages 95-106
  6. Epigenetics of Rheumatoid Arthritis

    • Aleksander M. Grabiec, Paul P. Tak, Kris A. Reedquist
    Pages 107-119
  7. DNA Methylation Changes in Osteoarthritis

    • Helmtrud I. Roach
    Pages 121-134
  8. Epigenetics and Type 2 Diabetes

    • Charlotte Ling, Tina Rönn, Marloes Dekker Nitert
    Pages 135-145
  9. Epigenetic Regulation of Asthma and Allergic Diseases

    • Andrew L. Durham, Ian M. Adcock
    Pages 147-161
  10. Epigenetics in Psychiatry

    • Hamid Mostafavi-Abdolmaleky, Stephen J. Glatt, Ming T. Tsuang
    Pages 163-174
  11. Epigenetics and Late-Onset Alzheimer’s Disease

    • Axel Schumacher, Syed Bihaqi, Nasser H. Zawia
    Pages 175-186
  12. Epigenetic Mechanisms in the Developmental Origins of Adult Disease

    • Keith M. Godfrey, Karen A. Lillycrop, Mark A. Hanson, Graham C. Burdge
    Pages 187-204
  13. Back Matter

    Pages 231-236

About this book

Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development. This book provides new insights into treatment, including modulation of epigenetic regulation. Each chapter gives an outline of a respective disease, explains why epigenetics may be involved in the disease process and then presents the evidence of how changes in epigenetic status contribute to initiation and progress of the disease. The final chapters look towards future therapeutic treatment, based on manipulation of epigenetic aspects. Written by widely published experts, Epigenetic Aspects of Chronic Diseases is a valuable reference tool for clinicians and researchers who investigate and treat chronic diseases, as well as health care personnel, post-doctoral fellows and medical or dental students.

Editors and Affiliations

  • , General Hospital, University of Southampton, Southampton, United Kingdom

    Helmtrud I. Roach

  • Health Center, Dept. Pharmacology, University of Connecticut, Farmington, USA

    Felix Bronner

  • Developmental Origins Health and Disease, University of Southampton, Southampton, United Kingdom

    Richard O.C. Oreffo

Bibliographic Information

  • Book Title: Epigenetic Aspects of Chronic Diseases

  • Editors: Helmtrud I. Roach, Felix Bronner, Richard O.C. Oreffo

  • DOI: https://doi.org/10.1007/978-1-84882-644-1

  • Publisher: Springer London

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag London Limited 2011

  • Hardcover ISBN: 978-1-84882-643-4Published: 02 April 2011

  • Softcover ISBN: 978-1-4471-5910-0Published: 26 September 2014

  • eBook ISBN: 978-1-84882-644-1Published: 01 April 2011

  • Edition Number: 1

  • Number of Pages: XVII, 236

  • Topics: Human Genetics, Medical Biochemistry, Internal Medicine

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access