Authors:
- Traces PPAR discovery through its history and to its modern state
- Paves the way for the development of safer and more effective PPAR modulators as therapeutic agents
- Serves as an excellent companion to Volume 952 of the Methods in Molecular Biology series
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Table of contents (10 chapters)
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Front Matter
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Back Matter
About this book
All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the history of PPAR discovery and detail the receptor structure and its posttranslational modifications. Furthermore, endogenous ligands as well as various classes of exogenous ligands, subtype-selective, dual and pan agonists as well as antagonists, are discussed. In addition, the tissue distribution and versatile functions of PPAR subtypes in major organs are described.
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As PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances aims to help researchers to develop safer and more effective PPAR modulators as therapeutic agents to treat a myriad of diseases and conditions.Authors and Affiliations
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School of Pharmacy, University of Missouri-Kansas City, Kansas City, USA
Jihan A. Youssef, Mostafa Z. Badr
Bibliographic Information
Book Title: Peroxisome Proliferator-Activated Receptors
Book Subtitle: Discovery and Recent Advances
Authors: Jihan A. Youssef, Mostafa Z. Badr
DOI: https://doi.org/10.1007/978-1-62703-420-3
Publisher: Humana Totowa, NJ
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media New York 2013
Hardcover ISBN: 978-1-62703-419-7Published: 19 April 2013
Softcover ISBN: 978-1-62703-886-7Published: 22 May 2015
eBook ISBN: 978-1-62703-420-3Published: 18 April 2013
Edition Number: 1
Number of Pages: IX, 137
Topics: Biochemistry, general, Receptors