Overview
- Closes the gap between appropriate methodologicol approaches and retrieval and anysis of ancient DNA
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 840)
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Table of contents (24 protocols)
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Front Matter
Keywords
About this book
Research into ancient DNA began more than 25 years ago with the publication of short mitochondrial DNA sequence fragments from the quagga, an extinct relative of the zebra. Ancient DNA research really gained momentum following the invention of PCR, which allowed millions of copies to be made of the few remaining DNA molecules preserved in fossils and museum specimens. In Ancient DNA: Methods and Protocols expert researchers in the field describe many of the protocols that are now commonly used to study ancient DNA. These include instructions for setting up an ancient DNA laboratory, extraction protocols for a wide range of different substrates, details of laboratory techniques including PCR and NGS library preparation, and suggestions for appropriate analytical approaches to make sense of the sequences obtained. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
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Authoritative and practical, Ancient DNA: Methods and Protocols seeks to aid scientists in the further study of ancient DNA and the methodological approaches in ancient research.
Editors and Affiliations
Bibliographic Information
Book Title: Ancient DNA
Book Subtitle: Methods and Protocols
Editors: Beth Shapiro, Michael Hofreiter
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-516-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2012
Hardcover ISBN: 978-1-61779-515-2Published: 16 January 2012
Softcover ISBN: 978-1-4939-5874-0Published: 23 August 2016
eBook ISBN: 978-1-61779-516-9Published: 13 January 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 247
Number of Illustrations: 14 b/w illustrations, 12 illustrations in colour
Topics: Human Genetics