Magnetic Resonance Neuroimaging

1. Front Matter

   Pages i-xiv

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2. Introduction

   1. Front Matter

      Pages 1-1

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   2. From Molecules to Man: The Dawn of a Vitreous Man

      • Michel Modo, Jeff W.M. Bulte

      Pages 3-14

3. General Techniques

   1. Front Matter

      Pages 15-15

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   2. Magnetic Resonance Safety

      • Andrew Simmons, Kristina Hakansson

      Pages 17-28

   3. Measuring the Absolute Water Content of the Brain Using Quantitative MRI

      • Nadim Joni Shah, Veronika Ermer, Ana-Maria Oros-Peusquens

      Pages 29-64

   4. Magnetic Resonance Relaxation and Quantitative Measurement in the Brain

      • Sean C.L. Deoni

      Pages 65-108

   5. Magnetic Resonance Brain Image Processing and Arithmetic with FSL

      • William R. Crum

      Pages 109-126

   6. Diffusion Tensor Imaging

      • Derek K. Jones, Alexander Leemans

      Pages 127-144

   7. Manganese-Enhanced Magnetic Resonance Imaging (MEMRI)

      • Cynthia A. Massaad, Robia G. Pautler

      Pages 145-174

   8. Sodium MRI

      • Ronald Ouwerkerk

      Pages 175-201

   9. MR Spectroscopy and Spectroscopic Imaging of the Brain

      • He Zhu, Peter B. Barker

      Pages 203-226

   10. Amide Proton Transfer Imaging of the Human Brain

       • Jinyuan Zhou

       Pages 227-237

   11. High-Field MRI of Brain Iron

       • Jozef H. Duyn

       Pages 239-249

   12. Magnetic Resonance Imaging-Based Mouse Brain Atlas and Its Applications

       • Manisha Aggarwal, Jiangyang Zhang, Susumu Mori

       Pages 251-270

   13. CEST MRI Reporter Genes

       • Guanshu Liu, Jeff W.M. Bulte, Assaf A. Gilad

       Pages 271-280

   14. Longitudinal Functional Magnetic Resonance Imaging in Animal Models

       • Afonso C. Silva, Junjie V. Liu, Yoshiyuki Hirano, Renata F. Leoni, Hellmut Merkle, Julie B. Mackel et al.

       Pages 281-302

   15. Combining EEG and fMRI

       • Karen Mullinger, Richard Bowtell

       Pages 303-326

   16. MR Angiography and Arterial Spin Labelling

       • David Thomas, Jack Wells

       Pages 327-345

4. Specific Applications

   1. Front Matter

      Pages 347-347

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The advent of non-invasive imaging technology, such as magnetic resonance imaging (MRI), has allowed biologists and clinicians to make great strides in unraveling the secrets of the brain. In Magnetic Resonance Neuroimaging: Methods and Protocols, expert researchers in the field provide a comprehensive collection of experimental MRI protocols that can be used to non-invasively interrogate the healthy and diseased brain. The chapters are divided into general techniques, such as the measurement of relaxivity, magnetic resonance spectroscopy, diffusion tensor imaging, and MR reporter genes, as well as specific applications in brain imaging, for example, phenotyping transgenic animals, detecting amyloid plaques, and fMRI in psychiatry. As a volume in the highly successful Methods in Molecular Biology™ series, this work contains the type of detailed description and implementation advice that is crucial for getting optimal results. Thorough and cutting-edge, Magnetic Resonance Neuroimaging: Methods and Protocols serves neuroscientists, clinical neurologists, psychiatrists, and radiologists with an excellent compendium of methods easily applied to both animal and human studies and certain to be an excellent resource for translational research.

• Living human brain
• MRI
• Neurology
• Neuroscience
• Translational studies

• Institute of Psychiatry, Department of Neuroscience, King's College London, London, United Kingdom

  Michel Modo

• Institute of Cell Engineering, Dept Radiology & Radiological Sciences, Johns Hopkins Univ. Sch. of Med., Baltimore, USA

  Jeff W.M. Bulte

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