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Anticoagulants, Antiplatelets, and Thrombolytics

  • Book
  • © 2010

Overview

Editors:
  1. Shaker A. Mousa

    1. , Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sc, Rensselaer, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Fully updates the popular original edition with cutting-edge approaches
  • Provides easy-to-use, readily reproducible protocols
  • Includes expert tips on troubleshooting and avoiding common pitfalls
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 663)

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Table of contents (13 protocols)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. In Vitro Methods of Evaluating Antithrombotics and Thrombolytics

    • Shaker A. Mousa
    Pages 1-28

  3. In Vivo Models for the Evaluation of Antithrombotics and Thrombolytics

    • Shaker A. Mousa
    Pages 29-107

  4. Heparin and Low-Molecular Weight Heparins in Thrombosis and Beyond

    • Shaker A. Mousa
    Pages 109-132

  5. Laboratory Methods and Management of Patients with Heparin-Induced Thrombocytopenia

    • Margaret Prechel, Walter P. Jeske, Jeanine M. Walenga
    Pages 133-156

  6. Novel Anticoagulant Therapy: Principle and Practice

    • Shaker A. Mousa
    Pages 157-179

  7. Oral Direct Factor Xa Inhibitors, with Special Emphasis on Rivaroxaban

    • Shaker A. Mousa
    Pages 181-201

  8. Antiplatelet Therapies: Drug Interactions in the Management of Vascular Disorders

    • Shaker A. Mousa
    Pages 203-219

  9. Prasugrel: A Novel Platelet ADP P2Y12 Receptor Antagonist

    • Shaker A. Mousa, Walter P. Jeske, Jawed Fareed
    Pages 221-228

  10. Antithrombotic Effects of Naturally Derived Products on Coagulation and Platelet Function

    • Shaker A. Mousa
    Pages 229-240

  11. Assessment of Anti-Metastatic Effects of Anticoagulant and Antiplatelet Agents Using Animal Models of Experimental Lung Metastasis

    • Ali Amirkhosravi, Shaker A. Mousa, Mildred Amaya, Todd Meyer, Monica Davila, Theresa Robson et al.
    Pages 241-259

  12. Adhesion Molecules: Potential Therapeutic and Diagnostic Implications

    • Shaker A. Mousa
    Pages 261-276

  13. Pharmacogenomics in Thrombosis

    • Shaker A. Mousa
    Pages 277-289

  14. Diagnosis and Management of Sickle Cell Disorders

    • Shaker A. Mousa, Mohamad H. Qari
    Pages 291-307

  15. Back Matter

    Pages 309-316
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Keywords

About this book

During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.

Reviews

From the reviews of the second edition:

“Text thoroughly presented the subject of antithrombotic and anticoagulant therapy in great depth and with complete review of the subject. In 13 chapters outstanding experts in their field have provided the cardiovascular specialist, hematologist, and pathologist with a thorough updating of the pharmacology of antithrombotic and anticoagulant therapy. … text should provide anyone working in the field of cardiovascular medicine or surgery and in hematology or pathology with a way to keep current with developments in the field of cardiovascular pharmacology. We recommend it highly.” (Harry L. Messmore and William H. Wehrmacher, Clinical and Applied Thrombosis/Hemostasis, November, 2010)

“Recent advances in testing and use of anticoagulants, antiplatelets, and thrombolytics and the essentials of efficacy testing, novel direct thrombin inhibitors, use of naturally-derived products, and pharmacogenomics in thrombosis. … The book is likely to be of interest to both academic scientists and practitioners interested in the treatment of patients with thrombosis. … This is very likely to make it onto the shelf in our laboratory, in particular as a reference for current advances in antithrombotics and thrombolytics.” (James P. Luyendyk, Doody’s Review Service, December, 2010)

Editors and Affiliations

  • , Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sc, Rensselaer, USA

    Shaker A. Mousa

Bibliographic Information

  • Book Title: Anticoagulants, Antiplatelets, and Thrombolytics

  • Editors: Shaker A. Mousa

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-60761-803-4

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-60761-802-7Published: 17 August 2010

  • Softcover ISBN: 978-1-4939-6097-2Published: 23 August 2016

  • eBook ISBN: 978-1-60761-803-4Published: 09 July 2010

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XI, 316

  • Topics: Molecular Medicine, Cardiology

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