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Adult Acute Lymphocytic Leukemia

Biology and Treatment

  • Book
  • © 2011

Overview

  • Focused on acute lymphocytic leukemia in adults
  • Explores current controversies in treatment
  • Discusses the indications for allogeneic bone marrow transplantation
  • Examines the factors influencing treatment decisions
  • Provides expert insight on discoveries in new molecular strategies and treatment

Part of the book series: Contemporary Hematology (CH)

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Table of contents (24 chapters)

Keywords

About this book

The current explosion of new areas of controversy in the treatment of acute lymphocytic leukemia in adults and young adults makes this comprehensive book a much needed reference for hematologists and oncologists. This book assembles leading authorities from around the globe to cover the full spectrum of ALL subtypes and their treatments. Specific topics of discussion include indications for allogeneic bone marrow transplant in first complete remission, the role of minimal residual disease in making treatment decisions, the treatment of young adults, and the treatment of Philadelphia chromosome positive ALL with the advent of the tyrosine kinase inhibitors. This is the first book to focus exclusively on the adult ALL patient. It provides a complete overview of diagnosis, molecular pathogenesis, evaluation, and treatment for this important patient population.

Reviews

From the reviews:

“The focus of this book is on acute lymphocytic leukemia in adults, with frequent allusions to the childhood form of disease. … the only recent text solely focused on acute lymphocytic leukemia as it relates to subtypes of disease in each of the adult age groups. It is up to date and well referenced, and it integrates basic, translational, and clinical science. As such it serves as a unique resource for scientists and clinicians in the field of acute lymphocytic leukemia.” (Paulette Mehta, Journal of the American Medical Association, June, 2011)

“Twenty-three chapters cover a range of clinically biased topics, from diagnosis and epidemiology to assessment of response to therapy, salvage protocols and the late effects of successful therapy. The text is broken up by tables, graphs and occasional colour illustrations, while extensive lists of references supplement each chapter. … A section on the biology of ALL helps to explain the diversity and underlying genetic instability of the disease. … this collection of reviews will prove to be a very useful supplementary reference text.” (Maria H. Gilleece, Bulletin of the Royal College of Pathologists, April, 2012)

Editors and Affiliations

  • Cleveland Clinic Foundation, Cleveland, USA

    Anjali S. Advani

  • School of Medicine, University Hospitals of Cleveland, Cleveland, USA

    Hillard M. Lazarus

Bibliographic Information

  • Book Title: Adult Acute Lymphocytic Leukemia

  • Book Subtitle: Biology and Treatment

  • Editors: Anjali S. Advani, Hillard M. Lazarus

  • Series Title: Contemporary Hematology

  • DOI: https://doi.org/10.1007/978-1-60761-707-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-706-8Published: 19 November 2010

  • Softcover ISBN: 978-1-4939-5766-8Published: 23 August 2016

  • eBook ISBN: 978-1-60761-707-5Published: 18 November 2010

  • Edition Number: 1

  • Number of Pages: XVI, 388

  • Topics: Hematology, Oncology

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