Overview
- Provides an easily accessible reference volume for methods used to evaluate vaccine adjuvants written by leading researchers in the field
- Presents methods to evaluate different aspects of the mechanism of action of vaccine adjuvants
- Covers a wide range of in vitro and in vivo assays for vaccine adjuvant activity
- Presents an approach based on the results of adjuvant activity, covering in vitro and in vivo model biological systems and approaches to data analysis
- Includes methods to evaluate novel materials with potential activity as vaccine adjuvants
- Serves as a comprehensive guide to developing, running, and analyzing the assays and model systems needed to study the activity of vaccine adjuvants
Part of the book series: Methods in Molecular Biology (MIMB, volume 626)
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Table of contents (19 protocols)
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Front Matter
Keywords
About this book
Spanning from discoveries in fundamental immunology to industrial and commercial concerns, the study of vaccine adjuvants has developed into an exciting area of work with great, vital potential in innovating techniques in which adjuvants may steer the immune system towards the responses required by unmet vaccination needs. In Vaccine Adjuvants: Methods and Protocols, expert researchers in the field provide clear and concise guidance on how to go about assessing the activity of adjuvant products. Rather than describing individual adjuvants, the volume strives to include detailed, practical information on measuring the responses produced by adjuvants in order to be relevant to the widest array of experiments. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and versatile, Vaccine Adjuvants: Methods and Protocols will enable those already pursuing vaccine adjuvant research, while also serving to stimulate discussion on how to best standardize adjuvant testing in order to facilitate meaningful comparisons, and above all, to aid in the prediction of which new products will most effectively and safely help to solve the current challenges in vaccination.
Editors and Affiliations
Bibliographic Information
Book Title: Vaccine Adjuvants
Book Subtitle: Methods and Protocols
Editors: Gwyn Davies
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60761-585-9
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2010
Hardcover ISBN: 978-1-60761-584-2Published: 08 February 2010
Softcover ISBN: 978-1-4939-5711-8Published: 23 August 2016
eBook ISBN: 978-1-60761-585-9Published: 23 January 2010
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 314
Topics: Immunology, Vaccine