Skip to main content
  • Book
  • © 2009

Biosensors and Biodetection

Methods and Protocols Volume 1: Optical-Based Detectors

  • Unique, one-of-a-kind laboratory manual for detailed, standardized protocols on biosensors or lab-on-a-chip technology
  • Describes basic types and the basic elements of biosensors from an experimental point of view
  • Provides multiple experimental approaches to enable readers to choose an appropriate design and to combine elements from different designs
  • Includes enough technical information to promote understanding of the technology and the ability to conduct similar experiments

Part of the book series: Methods in Molecular Biology (MIMB, volume 503)

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (25 protocols)

  1. Front Matter

    Pages i-xviii
  2. Optical-Based Detectors

    1. Surface Plasmon Resonance and Surface Plasmon Field-Enhanced Fluorescence Spectroscopy for Sensitive Detection of Tumor Markers

      • Yusuke Arima, Yuji Teramura, Hiromi Takiguchi, Keiko Kawano, Hidetoshi Kotera, Hiroo Iwata
      Pages 3-20
    2. Optical Biosensors Based on Photonic Crystal Surface Waves

      • Valery N. Konopsky, Elena V. Alieva
      Pages 49-64
    3. Surface Plasmon Resonance Biosensing

      • Marek Piliarik, Hana Vaisocherová, Jiří Homola
      Pages 65-88
    4. Label-Free Detection with the Resonant Mirror Biosensor

      • Mohammed Zourob, Souna Elwary, Xudong Fan, Stephan Mohr, Nicholas J. Goddard
      Pages 89-138
    5. Label-Free Detection with the Liquid Core Optical Ring Resonator Sensing Platform

      • Ian M. White, Hongying Zhu, Jonathan D. Suter, Xudong Fan, Mohammed Zourob
      Pages 139-165
    6. Reflectometric Interference Spectroscopy

      • Guenther Proll, Goran Markovic, Lutz Steinle, Guenter Gauglitz
      Pages 167-178
    7. Label-Free Serodiagnosis on a Grating Coupler

      • Thomas Nagel, Ehrentreich-Förster Eva, Frank F. Bier
      Pages 189-200
  3. Indirect Detectors

    1. CCD Camera Detection of HIV Infection

      • John R. Day
      Pages 203-219
    2. Simple Luminescence Detector for Capillary Electrophoresis

      • Antonio Segura-Carretero, Jorge F. Fernández-Sánchez, Alberto Fernández-Gutiérrez
      Pages 221-237
    3. Optical System Design for Biosensors Based on CCD Detection

      • Douglas A. Christensen, James N. Herron
      Pages 239-258
    4. A Simple Portable Electroluminescence Illumination-Based CCD Detector

      • Yordan Kostov, Nikolay Sergeev, Sean Wilson, Keith E. Herold, Avraham Rasooly
      Pages 259-272
    5. Fluoroimmunoassays Using the NRL Array Biosensor

      • Joel P. Golden, Kim E. Sapsford
      Pages 273-292
    6. DNA Analysis with a Photo-Diode Array Sensor

      • Hideki Kambara, Guohua Zhou
      Pages 337-360

About this book

Biosensors combine biological recognition elements and signal conversion elements into a biodetection system. They have been developed for a wide variety of biodetection applications, offering the advantages of increased speed and ease of use compared to traditional detection methods. In Biosensors and Biodetection: Methods and Protocols, leading experts describe the major technologies in the field in extensive technical detail, allowing readers both to understand the technology and to construct similar devices. Volume 1: Optical-Based Detectors delves into direct and indirect optical detectors, including methods involving surface plasmon resonance, interferometric sensors, CCD based detectors, and spectrometers, among many other cutting-edge technologies. Written in the highly successful Methods in Molecular Biologyâ„¢ series format, chapters include brief introductions to the subjects, lists of the necessary materials, step-by-step, readily reproducible protocols, and Notes sections, which highlight tips on troubleshooting and avoiding known pitfalls.

Comprehensive and up-to-date, Biosensors and Biodetection: Methods and Protocols is an ideal, user-friendly guide to this vital, versatile technology and a perfect tool for those who wish to further the field.

Reviews

From the reviews:

"This is a well written, comprehensive and up-to-date, user-friendly guide to essential information about direct and indirect optical detectors … . the book is written for engineering, chemical and physical science researchers who are developing biosensing technologies, as well as biologists and clinicians. It is also useful as a teaching tool for bioengineering, biomedical engineering, and biology faculty and students. … The clarity of the explanations of important and complex topics and the user friendly quality of the book make it unique." (Omer Iqbal, Doody’s Review Service, February, 2009)

Editors and Affiliations

  • FDA Center for Devices and Radiological Health, Silver Spring, USA

    Avraham Rasooly

  • National Cancer Institute, Bethesda, USA

    Avraham Rasooly

  • Fischell Department of Bioengineering, University of Maryland, College Park, USA

    Keith E. Herold

Bibliographic Information

  • Book Title: Biosensors and Biodetection

  • Book Subtitle: Methods and Protocols Volume 1: Optical-Based Detectors

  • Editors: Avraham Rasooly, Keith E. Herold

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-60327-567-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2009

  • Hardcover ISBN: 978-1-60327-566-8Published: 10 December 2008

  • Softcover ISBN: 978-1-61737-911-6Published: 19 November 2010

  • eBook ISBN: 978-1-60327-567-5Published: 17 January 2009

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVIII, 452

  • Topics: Biotechnology, Imaging / Radiology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access