Skip to main content
SpringerLink
Log in
Book cover

Asymptomatic Atherosclerosis

Pathophysiology, Detection and Treatment

  • Book
  • © 2011

Overview

Editors:
  1. Morteza Naghavi

    1. Endothelix, Inc., Houston, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents new multipronged strategies to aid in the early detection and treatment of asymptomatic atherosclerosis
  • Outlines more accurate measures of defining subclinical atherosclerosis, including coronary artery calcium scanning and carotid intima-media thickness measurement.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Cardiology (CONCARD)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 229.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (55 chapters)

  1. Front Matter

    Pages i-xxii
    Download chapter PDF

  2. Methods for the Detection of Subclinical Atherosclerotic Cardiovascular Disease

    1. Front Matter

      Pages 87-87
      Download chapter PDF

    1. Preventive Cardiology: The SHAPE of the Future

      • Morteza Naghavi
      Pages 1-12

    2. From Vulnerable Plaque to Vulnerable Patient

      • Morteza Naghavi, Erling Falk
      Pages 13-38

    3. Pathology of Vulnerability Caused by High-Risk (Vulnerable) Arteries and Plaques

      • Troels Thim, Mette Kallestrup Hagensen, Jacob Fog Bentzon, Erling Falk
      Pages 39-51

    4. Pathophysiology of Vulnerability Caused by Thrombogenic (Vulnerable) Blood

      • Giovanni Cimmino, Borja Ibanez, Juan Jose Badimon
      Pages 53-66

    5. Vulnerability Caused by Arrhythmogenic Vulnerable Myocardium

      • Ariel Roguin
      Pages 67-76

    6. Approach to Atherosclerosis as a Disease: Primary Prevention Based on the Detection and Treatment of Asymptomatic Atherosclerosis

      • Morteza Naghavi, Erling Falk, Khurram Nasir, Harvey S. Hecht, Matthew J. Budoff, Zahi A. Fayad et al.
      Pages 77-85

  4. Methods for the Detection of Subclinical Atherosclerotic Cardiovascular Disease

    1. Front Matter

      Pages 87-87
      Download chapter PDF

    2. History of the Evolution of Cardiovascular Risk Factors and the Predictive Value of Traditional Risk-Factor-Based Risk Assessment

      • Amit Khera
      Pages 89-105

    3. Comprehensive Lipid Profiling Beyond LDL

      • Benoit J. Arsenault, S. Matthijs Boekholdt, John J. P. Kastelein, Jean-Pierre Després
      Pages 107-118

    4. New Blood Biomarkers of Inflammation and Atherosclerosis

      • Natalie Khuseyinova, Wolfgang Koenig
      Pages 119-133

    5. Genomics and Proteomics: The Role of Contemporary Biomolecular Analysis in Advancing the Knowledge of Atherosclerotic Coronary Artery Disease

      • Gary P. Foster, Naser Ahmadi
      Pages 135-149

    6. Circulating Endothelial Progenitor Cells: Mechanisms and Measurements

      • Jonathan R. Murrow, Arshed A. Quyyumi
      Pages 151-167

    7. Family History: An Index of Genetic and Environmental Predisposition to Coronary Artery Disease

      • Shivda Pandey, Khurram Nasir
      Pages 169-178

    8. Endothelial Activation Markers in Sub-clinical Atherosclerosis: Insights from Mechanism-Based Paradigms

      • Victoria L. M. Herrera, Joseph A. Vita
      Pages 179-194

  5. Non Invasive, Non Imaging, Assessment of Atherosclerotic Cardiovascular Disease

    1. Front Matter

      Pages 195-195
      Download chapter PDF

    2. Exercise Stress Testing in Asymptomatic Individuals and Its Relation to Subclinical Atherosclerotic Cardiovascular Disease

      • Kevin S. Heffernan
      Pages 197-210

    3. The Ankle Brachial Index

      • Matthew A. Allison, Mary M. McDermott
      Pages 211-223

    4. Arterial Elasticity/Stiffness

      • Daniel A. Duprez, Jay N. Cohn
      Pages 225-235
Back to top

About this book

Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication (SHAPE) present a new paradigm for the screening and primary prevention of asymptomatic atherosclerosis. The text focuses on accurate, yet underutilized, measures of subclinical atherosclerosis, notably coronary artery calcium scanning and carotid intima-media thickness measurement. The authors introduce a comprehensive approach to identifying the vulnerable patients (asymptomatic individuals at risk of a near future adverse event). Additional chapters discuss future directions towards containing the epidemic of atherosclerotic cardiovascular disease using innovative solutions such as preemptive interventional therapies (bioabsorbable stents) for stabilization of vulnerable atherosclerotic plaques, mass unconditional Polypill therapy for population-based risk reduction, and ultimately vaccination strategies to prevent the development of atherosclerosis. Up-to-date and authoritative, Asymptomatic Atherosclerosis: Pathophysiology, Detection, and Treatment is a must-have for any cardiologist or primary care physician who wishes to practice modern preventive cardiology and manage the increasing number of asymptomatic atherosclerotic patients. Outlines more accurate measures of risk (coronary artery calcium and carotid intima-media thickness) than traditional risk factors (total cholesterol, LDL cholesterol, HDL cholesterol) Presents new multipronged strategies to aid in the early detection and treatment of high risk asymptomatic patients

Reviews

From the reviews:

“This book explores the latest developments in a multipronged preventive strategy to detect and treat asymptomatic patients at risk for future cardiovascular events based on severity of atherosclerosis … . will be of interest to medical students, allied health professionals, and physicians in training while working to inspire a paradigm shift in the thinking of cardiologists and practitioners involved in the treatment of patients with cardiovascular disease. … is well written and researched.” (M. A. Thompson, Doody’s Review Service, June, 2010)

“Is it time for comprehensive therapists to change the way they predict heart attacks, strokes, and other atherosclerotic disorders as proposed by the group of prominent cardiologists from the Society for Heart Attack Prevention and Eradication (SHAPE)? Those proposals are beautifully described in this thoroughgoing unique new textbook. … Comprehensive therapists can contribute better to the controversy after study of the extensive contents of this innovative book.” (William H. Wehrmacher and Harry Messmore, Journal of Geriatric Cardiology, June, 2011)

Editors and Affiliations

  • Endothelix, Inc., Houston, USA

    Morteza Naghavi

Bibliographic Information

  • Book Title: Asymptomatic Atherosclerosis

  • Book Subtitle: Pathophysiology, Detection and Treatment

  • Editors: Morteza Naghavi

  • Series Title: Contemporary Cardiology

  • DOI: https://doi.org/10.1007/978-1-60327-179-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2011

  • Hardcover ISBN: 978-1-60327-178-3Published: 09 March 2010

  • Softcover ISBN: 978-1-62703-823-2Published: 30 November 2014

  • eBook ISBN: 978-1-60327-179-0Published: 01 July 2010

  • Series ISSN: 2196-8969

  • Series E-ISSN: 2196-8977

  • Edition Number: 1

  • Number of Pages: XXII, 737

  • Topics: Cardiology, Internal Medicine, General Practice / Family Medicine, Primary Care Medicine

Publish with us

Policies and ethics

Back to top

Search

Navigation