Stem Cells in Endocrinology

1. Front Matter

   Pages i-xiv

   PDF

2. Basic Stem Cell Biology

   1. Front Matter

      Pages 1-1

      PDF

   2. Embryonic Stem Cells

      • Victoria L. Browning, Jon S. Odorico

      Pages 3-22

   3. Germ Line Stem Cells

      • Makoto C. Nagano

      Pages 23-47

   4. Umbilical Cord Stem Cells

      • Kathy E. Mitchell

      Pages 49-65

   5. Differentiation Potential of Adult Stem Cells

      • Henry E. Young, Asa C. Black Jr.

      Pages 67-92

   6. Growth Conditions for Primate vs Murine Embryonic Stem Cells

      • Gillian M. Beattie, Nathan Bucay, Rohan Humphrey, Ana D. Lopez, Alberto Hayek

      Pages 93-111

3. Translational Research

   1. Front Matter

      Pages 113-113

      PDF

   2. Islet Precursor Cells in Adult Pancreatic Islets

      • Gladys Teitelman, Irem Nasir

      Pages 115-132

   3. Transcription Factor-Directed Differentiation of Stem Cells Along an Endocrine Lineage

      • William L. Lowe Jr.

      Pages 133-146

   4. Generation of Islet-Like Structures From ES Cells

      • Nadya Lumelsky

      Pages 147-163

   5. The Therapeutic Potential of Liver Repopulation for Metabolic or Endocrine Disorders

      • Sanjeev Gupta

      Pages 165-181

   6. The Manipulation of Mesenchymal Stem Cells for Bone Repair

      • Shelley R. Winn

      Pages 183-206

   7. Spermatogenesis From Transplanted Spermatogenic Stem Cells

      • Michael D. Griswold, Derek McLean

      Pages 207-219

   8. Hematopoietic Stem Cell Transplant in the Treatment of Autoimmune Endocrine Disease

      • Jody Schumacher, Ewa Carrier

      Pages 221-241

   9. Preclinical Trials for Stem Cell Therapy

      • Linda B. Lester, K. Y. Francis Pau, Don P. Wolf

      Pages 243-262

4. Back Matter

   Pages 263-273

   PDF

A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

• Diabetes
• Pancreatic Islets
• biology
• cell
• cell biology
• diseases
• endocrinology
• growth
• hematopoietic stem cell
• infertility
• spermatogenesis
• stem cells
• therapy
• transcription

From the reviews:

"Stem Cells in Endocrinology considers the potential use of stem cells for the treatment of endocrine disorders. It consists of two sections, Basic Stem Cell Biology and Translational Research. … The book as a whole is certainly of interest not only to specialists in the therapy of endocrine disorders, but also to those conducting stem cell research in general, and to motivated students." (Antonin Bukovsky, TRENDS in Endocrinology and Metabolism, Vol. 17 (6), August, 2006)

• Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, Oregon Health and Sciences University, Portland

  Linda B. Lester

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