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Visual Transduction And Non-Visual Light Perception

  • Book
  • © 2008

Overview

Editors:
  1. Joyce Tombran-Tink

    1. Department of Ophthalmology, Department of Neural and Behavioral Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, USA

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  2. Colin J. Barnstable

    1. Department of Ophthalmology, Department of Neural and Behavioral Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, USA

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  • Thorough explication of the phototransduction cascade
  • Comprehensive and multidisciplinary
  • Covers developmental, structural and molecular mechanisms
  • Leads to a more exhaustive understanding of ocular diseases and therapies

Part of the book series: Ophthalmology Research (OPHRES)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-x
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  2. Evolution of the Visual System

    1. An Organ of Exquisite Perfection

      • George Ayoub
      Pages 3-13

  3. Photoreceptor Structure, Function, and Development

    1. Development of the Foveal Specialization

      • Keely M. Bumsted O'Brien
      Pages 17-33

    2. An Update on the Regulation of Rod Photoreceptor Development

      • Edward M. Levine, Sabine Fuhrmann
      Pages 35-64

  4. The Retinal Pigment Epithelium and the Visual Cycle

    1. Photoreceptor—RPE Interactions

      • Silvia C. Finnemann, Yongen Chang
      Pages 67-86

    2. Molecular Biology of IRBP and Its Role in the Visual Cycle

      • Diane E. Borst, Jeffrey H. Boatright, John M. Nickerson
      Pages 87-122

  5. Visual Signaling in the Outer Retina

    1. Regulation of Photoresponses by Phosphorylation

      • Alecia K. Gross, Qiong Wang, Theodore G. Wensel
      Pages 125-140

    2. The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of Photoreceptor Phosphodiesterase (PDE6)

      • Rick H. Cote
      Pages 141-169

    3. Rhodopsin Structure, function, and Involvement in Retinitis Pigmentosa

      • Scott Gleim, John Hwa
      Pages 171-196

    4. Multiple Signaling Pathways Govern Calcium Homeostasis in Photoreceptor Inner Segments

      • Tamas Szikra, David Krizaj
      Pages 197-223

    5. The Transduction Channels of Rod and Cone Photoreceptors

      • Dimitri Tränkner
      Pages 225-249

    6. Rhodopsins in Drosophila Color Vision

      • David Jukam, Preet Lidder, Claude Desplan
      Pages 251-266

    7. INAD Signaling Complex of Drosophila Photoreceptors

      • Armin Huber, Nina E. Meyer
      Pages 267-284

  6. Visual Processing in the Inner Retina

    1. Visual Signal Processing in the Inner Retina

      • Botir T. Sagdullaev, Tomomi Ichinose, Erika D. Eggers, Peter D. Lukasiewicz
      Pages 287-304

  7. Color Vision and Adaptive Processes

    1. Human Cone Spectral Sensitivities and Color Vision Deficiencies

      • Andrew Stockman, Lindsay T. Sharpe
      Pages 307-327

    2. Luminous Efficiency Functions

      • Lindsay T. Sharpe, Andrew Stockman
      Pages 329-351

    3. Cone Pigments and Vision in the Mouse

      • Gerald H. Jacobs
      Pages 353-373

    4. Multifocal Oscillatory Potentials of the Human Retina

      • Anne Kurtenbach, Herbert Jägle
      Pages 375-388

  8. Aging and Vision

    1. The Aging of the Retina

      • Caren Bellmann, José A. Sahel
      Pages 391-402

    2. Aging of the Retinal Pigment Epithelium

      • Michael E. Boulton
      Pages 403-420
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Keywords

About this book

Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, The Visual Transduction Cascade: Basic and Clinical Principles reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths -- a good example of the limitations of the human sensory systems. Comprehensive and penetrating, The Visual Transduction Cascade: Basic and Clinical Principles brings together the developmental, structural, and molecular mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.

Editors and Affiliations

  • Department of Ophthalmology, Department of Neural and Behavioral Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, USA

    Joyce Tombran-Tink, Colin J. Barnstable

Bibliographic Information

  • Book Title: Visual Transduction And Non-Visual Light Perception

  • Editors: Joyce Tombran-Tink, Colin J. Barnstable

  • Series Title: Ophthalmology Research

  • DOI: https://doi.org/10.1007/978-1-59745-374-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2008

  • Hardcover ISBN: 978-1-58829-957-4Published: 25 August 2008

  • Softcover ISBN: 978-1-4939-6082-8Published: 23 August 2016

  • eBook ISBN: 978-1-59745-374-5Published: 11 August 2008

  • Edition Number: 1

  • Number of Pages: XI, 509

  • Topics: Ophthalmology, Cell Biology, Molecular Medicine

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