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Post-Transcriptional Gene Regulation

  • Book
  • © 2008

Overview

  • Step-by-step instructions that ensure successful results
  • Tricks of the trade and notes on troubleshooting and avoiding known pitfalls

Part of the book series: Methods in Molecular Biology (MIMB, volume 419)

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Table of contents (21 protocols)

  1. Bioinformatics

  2. Fundamental Aspects of the Study of RNA Biology

  3. Techniques for Specific Aspects of RNA Biology

Keywords

About this book

In Post-Transcriptional Gene Regulation, renowned authors present current technical approaches to most aspects of post-transcriptional control and provide a useful and versatile laboratory bench resource. With chapters split into sections covering bioinformatics, fundamental aspects of the study of RNA biology, and techniques for specific aspects of RNA biology, the expert authors have filled the book with invaluable tricks of the trade, perfected in their state-of-the-art laboratories.

This new volume from the Methods in Molecular Biology series is convinently divided into three sections. The first section presents a series of bioinformatic approaches to address the use of RNA databases and algorithms to the study of post-transcriptional regulation involving untranslated regions of transcripts. In the second section, a series of methods applicable to fundamental issues in mRNA biology are presented. These include RNA structure/function, mRNP analysis and novel methods for mRNA labeling and isolation. The third section of this volume presents methodologies to study particular aspects of post-transcriptional control. This section includes methods for the study of alternative splicing and 3’ end processing, mRNA localization, mRNA translation, mRNA stability and si/miRNA regulation. Collectively, Post-Transcriptional Gene Regulation provides the reader with a useful and versatile laboratory bench resource that will become an essential reference in the field.

Editors and Affiliations

  • Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, USA

    Jeffrey Wilusz

Bibliographic Information

  • Book Title: Post-Transcriptional Gene Regulation

  • Editors: Jeffrey Wilusz

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-59745-033-1

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2008

  • Hardcover ISBN: 978-1-58829-783-9Published: 14 December 2007

  • Softcover ISBN: 978-1-61737-776-1Published: 19 November 2010

  • eBook ISBN: 978-1-59745-033-1Published: 04 February 2008

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XVIII, 318

  • Number of Illustrations: 56 b/w illustrations

  • Topics: Biochemistry, general, Cell Biology, Human Genetics, Bioinformatics

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