Overview
- Editors:
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Visith Thongboonkerd
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Medical Molecular Biology Unit Office for Research and Development Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
- The first collection of applications of proteomics to analyze various human body fluids
- Provides basic principles and strategies for proteomic analysis of human body fluids
- Offers more details regarding methodologies and recent findings
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Table of contents (24 chapters)
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Front Matter
Pages i-xiii
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Principles of Proteomics Applied to Human Body Fluids
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- Sung-Min Ahn, Richard J. Simpson
Pages 3-30
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- Natalia Govorukhina, Rainer Bischoff
Pages 31-69
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- Silke Wittemann, Dominic P. Eisinger, Laurie L. Stephen, Thomas O. Joos
Pages 71-82
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- Jakob Bunkenborg, Per Hägglund, Ole Nørregaard Jensen
Pages 107-128
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- Malabika Sarker, G. Hanumanthu, Akhilesh Pandey
Pages 129-136
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- Christine Hoogland, Khaled Mostaguir, Jean-Charles Sanchez, Denis F. Hochstrasser, Ron D. Appel
Pages 137-146
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- Marc R. Wilkins, Sybille M. N. Hunt
Pages 147-174
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Proteomic Analysis of Specific Types of Human Body Fluids
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Front Matter
Pages 193-193
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Methods, Findings, applications, Perspectives, and Future Directions
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- Gilbert S. Omenn, Rajasree Menon, Marcin Adamski, Thomas Blackwell, Brian B. Haab, Weimin Gao et al.
Pages 195-224
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- Visith Thongboonkerd, Pedro R. Cutillas, Robert J. Unwin, Stefan Schaub, Peter Nickerson, Marion Haubitz et al.
Pages 225-268
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- Margareta Ramström, Jonas Bergquist
Pages 269-284
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- Joost Hegmans, Annabrita Hemmes, Bart Lambrecht
Pages 285-307
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- Ruddy Wattiez, Olivier Michel, Paul Falmagne
Pages 309-325
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- Begona Casado, Simona Viglio, James N. Baraniuk
Pages 327-346
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- Francisco M. L. Amado, Rui M. P. Vitorino, Maria J. C. Lobo, Pedro M. D. N. Domingues
Pages 347-376
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- Mads Grønborg, Anirban Maitra, Akhilesh Pandey
Pages 377-397
About this book
Rapid growth of the “proteomics” field during the past twelve years has c- tributed to significant advances in science. To date, proteomic technologies have been widely applied to examining various kinds of biological materials. Clinical proteomics is the concept of using proteomic techniques to evaluate the proteomes in clinical samples for biomarker discovery and for better understa- ing of normal physiology and pathogenic mechanisms of human diseases. Tra- lating the proteomic information to clinical practice may lead to the ultimate goals of earlier diagnosis, improved therapeutic outcome and successful prev- tion of diseases. Human body fluids are produced, secreted, and/or excreted from various tissues or organs. Major compositions of body fluids are water, organic s- stances and inorganic compounds. These compositions vary in each body fluid, making one’s function different from the others. Analyses of protein com- nents in individual fluids would increase current knowledge on the biology and physiology of various organ systems, and on the pathophysiology of diseases, which cause alterations in protein production, secretion, and/or excretion from the affected tissues or organs into the body fluids. Additionally, human body fluids are the main targets and valuable sources for biomarker discovery. As the high-throughput capability and applicability of proteomics for analyzing proteins in the body fluids have been already proven, these desires are most likely achievable by using proteomic technologies.
Editors and Affiliations
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Medical Molecular Biology Unit Office for Research and Development Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Visith Thongboonkerd
