Ocular Angiogenesis

1. Front Matter

   Pages i-xv

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2. Angiogenic Diseases

   1. Front Matter

      Pages 1-1

      PDF

   2. Age-Related Macular Degeneration

      • Curtis L. Hagedorn, Ron A. Adelman

      Pages 3-22

   3. Endogenous Angiogenic Inhibitors in Diabetic Retinopathy

      • Jian-Zing Ma, Sarah X. Zhang

      Pages 23-44

   4. Corneal Angiogenesis

      • Trevor R. Carmichael

      Pages 45-71

   5. Polypoidal Choroidal Vasculopathy

      • Nahoko Ogata, Kanji Takahashi

      Pages 73-84

   6. Myopic Choroidal Neovascularization

      • Kyoko Ohno-Matsui, Takashi Tokoro

      Pages 85-99

   7. Mechanisms of the Formation and Stability of Retinal Blood Vessels

      • Jonathan Stone, Trent Sandercoe, Jan Provis

      Pages 101-126

   8. Neovascular Glaucoma

      • James C. Tsai, M. Bruce Shields

      Pages 127-147

   9. Eales’ Disease

      • Jyotirmay Biswas

      Pages 149-159

   10. Angiogenesis and Ocular Tumorigenesis

       • Nader Sheibani, Daniel M. Albert

       Pages 161-171

   11. Genetics of Ocular Vascular Disease

       • Jacquie Greenberg, Ari Ziskind, Stephen P. Daiger

       Pages 173-188

3. Endogenous Promoters and Inhibitors of Angiogenesis

   1. Front Matter

      Pages 191-191

      PDF

   2. Vascular Endothelial Growth Factor and Retinal Diseases

      • Sam Dahr, Karl G. Csaky

      Pages 191-204

   3. The Role of Fibroblast Growth Factors in Ocular Angiogenesis

      • Andreas Bikfalvi, Sophie Javerzat

      Pages 205-213

   4. Control of Neovascularization and Cell Survival in the Eye by PEDF

      • Joyce Tombran-Tink, Colin J. Barnstable

      Pages 215-231

   5. Thrombospondin

      • Arin Aurora, Olga V. Volpert

      Pages 233-255

   6. Regulation of Ocular Angiogenesis by Matrix Proteases and Tissue Inhibitors of Metalloproteinases

      • Bela Anand-Apte

      Pages 257-277

   7. Integrins in Ocular Angiogenesis

      • Matthew R. Ritter, Martin Friedlander

      Pages 279-289

   8. Ocular Inflammation and Neovascularization

      • Chi-Chao Chan, Robert B. Nussenblatt

      Pages 291-305

Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

• eye
• glaucoma
• macular degeneration
• retina

From the reviews:

"Colin J. Barnstable and co-workers have undertaken the task to present an up-to-date collection including presentations on clinical and mechanistic data as well as current therapeutic applications. The 412-page hardback book includes numerous black-and-white pictures as well as several illustrations. … The book … will surely find a place not only for the use of basic scientists but could be of interest for the clinician trying to understand the background on angiogenesis research." (Antonia Joussen, Graefes Archive for Clinical and Experimental Ophthalmology, Issue 246, 2008)

• Division of Pharmaceutical Sciences, University of Missouri-Kansas City, Kansas City

  Joyce Tombrain-Tink

• Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven

  Joyce Tombrain-Tink, Colin J. Barnstable

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