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  • Book
  • © 2017

Prion Diseases

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Neuromethods (NM, volume 129)

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Table of contents (16 protocols)

  1. Front Matter

    Pages i-xv
  2. Kuru: Introduction to Prion Diseases

    • PaweÅ‚ P. Liberski, Agata Gajos
    Pages 1-31
  3. Anthropological Methods Used in Kuru Research

    • Shirley Lindenbaum
    Pages 33-48
  4. Nonhuman Primates in Research on Transmissible Spongiform Encephalopathies

    • David M. Asher, Pedro Piccardo, Luisa Gregori
    Pages 49-63
  5. Electron Microscopy of Prion Diseases

    • PaweÅ‚ P. Liberski
    Pages 123-143
  6. Cell Death and Autophagy in Prion Diseases

    • Pawel P. Liberski
    Pages 145-158
  7. Detection and Diagnosis of Prion Diseases Using RT-QuIC: An Update

    • Byron Caughey, Christina D. Orru, Bradley R. Groveman, Matilde Bongianni, Andrew G. Hughson, Lynne D. Raymond et al.
    Pages 173-181
  8. Exosomes in Prion Diseases

    • Alexander Hartmann, Hermann Altmeppen, Susanne Krasemann, Markus Glatzel
    Pages 197-207
  9. Synthetic Mammalian Prions

    • Fabio Moda, Edoardo Bistaffa, Joanna Narkiewicz, Giulia Salzano, Giuseppe Legname
    Pages 209-228
  10. Biomarkers in Cerebrospinal Fluid

    • Joanna Gawinecka, Matthias Schmitz, Inga Zerr
    Pages 229-252
  11. The Use of Transgenic and Knockout Mice in Prion Research

    • Abigail B. Diack, Jean C. Manson
    Pages 253-267
  12. Transgenic Mouse Models of Prion Diseases

    • Julie Moreno, Glenn C. Telling
    Pages 269-301
  13. Back Matter

    Pages 303-304

About this book

This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research.

Editors and Affiliations

  • Department of Molecular Pathology, Medical University of Lodz, Lodz, Poland

    Pawel P. Liberski

Bibliographic Information

  • Book Title: Prion Diseases

  • Editors: Pawel P. Liberski

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-4939-7211-1

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media LLC 2017

  • Hardcover ISBN: 978-1-4939-7209-8Published: 19 August 2017

  • Softcover ISBN: 978-1-4939-8417-6Published: 14 August 2018

  • eBook ISBN: 978-1-4939-7211-1Published: 18 August 2017

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XVI, 304

  • Number of Illustrations: 22 b/w illustrations, 27 illustrations in colour

  • Topics: Neurosciences

Buy it now

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access