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Glycobiology of the Nervous System

  • Book
  • © 2014

Overview

Editors:
  1. Robert K. Yu

    1. Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Georgia Regents University, Augusta, USA

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  2. Cara-Lynne Schengrund

    1. Department of Biochemistry and Molecular Biology, The Pennsylvania State University, College of Medicine, Hershey, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides an important overview of recent developments in the field of neural glycobiology
  • Chapters provided by leaders in the field
  • Can serve as a textbook for students and an important reference volume for researchers?

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 9)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Introduction to the Complexity of Cell Surface and Tissue Matrix Glycoconjugates

    • Veer P. Bhavanandan, D. Channe Gowda
    Pages 1-31

  3. Introduction to Cells Comprising the Nervous System

    • Douglas G. Peters, James R. Connor
    Pages 33-45

  4. Synthesis, Processing, and Function of N-glycans in N-glycoproteins

    • Erhard Bieberich
    Pages 47-70

  5. Synthesis of O-Linked Glycoconjugates in the Nervous System

    • Jin-Ichi Inokuchi, Shinji Go, Yoshio Hirabayashi
    Pages 71-87

  6. Chemistry and Function of Glycosaminoglycans in the Nervous System

    • Nancy B. Schwartz, Miriam S. Domowicz
    Pages 89-115

  7. Use of Glycan-Targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous System

    • Yasuhiko Kizuka, Kenji Kanekiyo, Shinobu Kitazume, Naoyuki Taniguchi
    Pages 117-127

  8. From Mass Spectrometry-Based Glycosylation Analysis to Glycomics and Glycoproteomics

    • Kay-Hooi Khoo
    Pages 129-164

  9. Structural Analysis of Oligosaccharides and Glycoconjugates Using NMR

    • Yoshiki Yamaguchi, Takumi Yamaguchi, Koichi Kato
    Pages 165-183

  10. Glycolipid and Glycoprotein Expression During Neural Development

    • Robert K. Yu, Yutaka Itokazu
    Pages 185-222

  11. Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System

    • Massimo Aureli, Maura Samarani, Valentina Murdica, Laura Mauri, Nicoletta Loberto, Rosaria Bassi et al.
    Pages 223-244

  12. Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous System

    • Pablo H. H. Lopez
    Pages 245-262

  13. Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a Glycosynapse

    • Joan M. Boggs
    Pages 263-291

  14. Glycosignaling: A General Review

    • Glyn Dawson
    Pages 293-306

  15. Glycosphingolipids in the Regulation of the Nervous System

    • Koichi Furukawa, Yusuke Ohmi, Yuki Ohkawa, Orie Tajima, Keiko Furukawa
    Pages 307-320

  16. Glycobiology of Ion Transport in the Nervous System

    • Martha C. Nowycky, Gusheng Wu, Robert W. Ledeen
    Pages 321-342

  17. O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration

    • Olof Lagerlöf, Gerald W. Hart
    Pages 343-366

  18. N-Glycosylation in Regulation of the Nervous System

    • Hilary Scott, Vladislav M. Panin
    Pages 367-394

  19. Roles of Carbohydrates in the Interaction of Pathogens with Neural Cells

    • Cara-Lynne Schengrund
    Pages 395-413

  20. Glycoconjugate Changes in Aging and Age-Related Diseases

    • Susumu Ando
    Pages 415-447
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Keywords

About this book

A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.

Editors and Affiliations

  • Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Georgia Regents University, Augusta, USA

    Robert K. Yu

  • Department of Biochemistry and Molecular Biology, The Pennsylvania State University, College of Medicine, Hershey, USA

    Cara-Lynne Schengrund

About the editors

Cara-Lynne Schengrund, PhD, is Professor Emeritus, Department of Biochemistry and Molecular Biology, Penn State University, Hershey, Pennsylvania


Robert K. Yu, PhD, Med ScD, is Professor, Department of Neuroscience and Regenerative Medicine, and GRA Eminent Scholar in Molecular and Cellular Neurobiology, Medical College of Georgia at Augusta University, Augusta, Georgia




Bibliographic Information

  • Book Title: Glycobiology of the Nervous System

  • Editors: Robert K. Yu, Cara-Lynne Schengrund

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-1-4939-1154-7

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Softcover ISBN: 978-1-4939-4637-2Published: 10 September 2016

  • eBook ISBN: 978-1-4939-1154-7Published: 23 August 2014

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: XVII, 584

  • Number of Illustrations: 64 b/w illustrations, 59 illustrations in colour

  • Topics: Neurosciences, Neurobiology, Neurochemistry

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