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Cell Cycle Control

Mechanisms and Protocols

  • Book
  • © 2014

Overview

Editors:
  1. Eishi Noguchi

    1. Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Mariana C. Gadaleta

    1. Dept of Biochemistry & Molecular Biology, Drexel University College of Medicine, Philadelphia, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1170)

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Table of contents (34 protocols)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Reviews: Cell Cycle Regulations

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Cell Cycle-Regulated Transcription: Effectively Using a Genomics Toolbox

      • Sara L. Bristow, Adam R. Leman, Steven B. Haase
      Pages 3-27

    3. Cell Cycle Regulation by Checkpoints

      • Kevin J. Barnum, Matthew J. O’Connell
      Pages 29-40

    4. Interplay Between the Cell Cycle and Double-Strand Break Response in Mammalian Cells

      • Kate Beishline, Jane Azizkhan-Clifford
      Pages 41-59

    5. Cell Cycle Regulation by Protein Degradation

      • Deanna M. Koepp
      Pages 61-73

    6. Linking Chromosome Duplication and Segregation via Sister Chromatid Cohesion

      • Adam R. Leman, Eishi Noguchi
      Pages 75-98

    7. The Greatwall–PP2A Axis in Cell Cycle Control

      • Peng Wang, Marcos Malumbres, Vincent Archambault
      Pages 99-111

    8. Cell Cycle Regulation by the Nutrient-Sensing Mammalian Target of Rapamycin (mTOR) Pathway

      • Elisabet Cuyàs, Bruna Corominas-Faja, Jorge Joven, Javier A. Menendez
      Pages 113-144

    9. The Senescence Arrest Program and the Cell Cycle

      • Alessandro Bitto, Elizabeth P. Crowe, Chad Lerner, Claudio Torres, Christian Sell
      Pages 145-154

    10. Oncogenic Ras Pushes (and Pulls) Cell Cycle Progression Through ERK Activation

      • Paul M. Campbell
      Pages 155-163

    11. Cell Cycle Regulation During Viral Infection

      • Sumedha Bagga, Michael J. Bouchard
      Pages 165-227

    12. The Roles of Cohesins in Mitosis, Meiosis, and Human Health and Disease

      • Amanda S. Brooker, Karen M. Berkowitz
      Pages 229-266

    13. Introductory Review of Computational Cell Cycle Modeling

      • Andres Kriete, Eishi Noguchi, Christian Sell
      Pages 267-275

  3. Protocols: Analyzing Cell Cycle Regulations

    1. Front Matter

      Pages 277-277
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    2. Cell Cycle Synchronization and Flow Cytometry Analysis of Mammalian Cells

      • Naoko Yoshizawa-Sugata, Hisao Masai
      Pages 279-293

    3. Analyzing Transcription Dynamics During the Budding Yeast Cell Cycle

      • Adam R. Leman, Sara L. Bristow, Steven B. Haase
      Pages 295-312

    4. Analyzing Cell Cycle Checkpoints in Response to Ionizing Radiation in Mammalian Cells

      • Bin Wang
      Pages 313-320

    5. Analyzing DNA Replication Checkpoint in Budding Yeast

      • Nicole Hustedt, Kenji Shimada
      Pages 321-341

    6. Analyzing Cell Cycle-Dependent Degradation and Ubiquitination in Budding Yeast

      • Dong-Hwan Kim, Deanna M. Koepp
      Pages 343-356
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Keywords

About this book

A collection of new reviews and protocols from leading experts in cell cycle regulation, Cell Cycle Control: Mechanisms and Protocols, Second Edition presents a comprehensive guide to recent technical and theoretical advancements in the field. Beginning with the overviews of various cell cycle regulations, this title presents the most current protocols and state-of-the-art techniques used to generate latest findings in cell cycle regulation, such as protocols to analyze cell cycle events and molecules. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Cell Cycle Control: Mechanisms and Protocols, Second Edition will be a valuable resource for a wide audience, ranging from the experienced cell cycle researchers looking for new approaches to the junior graduate students giving their first steps in cell cycle research.

Editors and Affiliations

  • Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, USA

    Eishi Noguchi

  • Dept of Biochemistry & Molecular Biology, Drexel University College of Medicine, Philadelphia, USA

    Mariana C. Gadaleta

Bibliographic Information

  • Book Title: Cell Cycle Control

  • Book Subtitle: Mechanisms and Protocols

  • Editors: Eishi Noguchi, Mariana C. Gadaleta

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-0888-2

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4939-0887-5Published: 07 June 2014

  • Softcover ISBN: 978-1-4939-4728-7Published: 23 August 2016

  • eBook ISBN: 978-1-4939-0888-2Published: 06 June 2014

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XIV, 623

  • Number of Illustrations: 39 b/w illustrations, 62 illustrations in colour

  • Topics: Cell Biology, Cell Cycle Analysis

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