Fat-Soluble Vitamins

1. Front Matter

   Pages i-xxvi

   PDF

2. Vitamin A

   1. Front Matter

      Pages 1-1

      PDF

   2. Control of Retinoid Nuclear Receptor Function and Expression

      • Richard M. Niles

      Pages 3-28

   3. Retinoid Endocrinology

      • Amandio V. Vieira

      Pages 29-51

   4. Structure and Function of Retinoid-Binding Proteins

      • Marcia E. Newcomer, R. Scott Jamison, David E. Ong

      Pages 53-80

   5. The Role of Retinoids in Developmental Mechanisms in Embryos

      • Malcolm Maden

      Pages 81-111

   6. Antioxidant Activity of Vitamin A within Lipid Environments

      • Maria A. Livrea, Luisa Tesoriere

      Pages 113-143

   7. Plasma Vitamins A and E in HIV-Positive Patients

      • Joël Constans, Evelyne Peuchant, Claire Sergeant, Claude Conri

      Pages 145-155

3. Carotenoids

   1. Front Matter

      Pages 157-157

      PDF

   2. The Bioconversion of β-Carotene into Retinoids

      • Xiang-Dong Wang, Norman I. Krinsky

      Pages 159-180

   3. The Role of Carotenoids in Modulating DNA Stability and Lipid Peroxidation

      • Susan J. Duthie, Andrew R. Collins, Garry G. Duthie

      Pages 181-207

   4. β-Carotene

      • Billy W. Day, Stefania Bergamini, Yulia Y. Tyurina, Gianfranca Carta, Vladimir A. Tyurin, Valerian E. Kagan

      Pages 209-217

   5. Biophysical Properties of Carotenoids

      • Maria Tomoaia-Cotisel, Peter J. Quinn

      Pages 219-242

4. Vitamin D

   1. Front Matter

      Pages 243-243

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   2. The Role of Vitamin D3 and Antiestrogens in Modulating Apoptosis of Breast Cancer Cells and Tumors

      • JoEllen Welsh, Kathryn VanWeelden, Louise Flanagan, Ian Byrne, Elizabeth Nolan, Carmen J. Narvaez

      Pages 245-270

   3. Vitamin D and Intracellular Calcium

      • Igor N. Sergeev, William B. Rhoten, Vladimir B. Spirichev

      Pages 271-297

5. Vitamin E

   1. Front Matter

      Pages 299-299

      PDF

   2. Antioxidant Chemistry of α-Tocopherol in Biological Systems

      • Daniel C. Liebler

      Pages 301-317

   3. Localization of Vitamin E in Membranes

      • Peter J. Quinn

      Pages 319-343

   4. The Molecular Action of α-Tocopherol in Lipoprotein Lipid Peroxidation

      • P. K. Witting, J. M. Upston, R. Stocker

      Pages 345-390

The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan­ sion of our knowledge of its role in cell biology, genetics, and disease. The level of our understanding has clearly moved from knowing what fat­ soluble vitamins do to how they perform their functions. Hand in hand with a knowledge of their molecular mechanisms of action is the recognition that vitamins are used sparingly, and regeneration processes operate in certain cases to recycle vitamins from their metabolites. We have divided the volume into alphabetical sections beginning with vitamin A and the carotenoids through vitamins D, E, F, and K, and ending with coenzyme Q. The contributors are all acknowledged experts in their particular fields and have made significant contributions to published research results. All have worked assiduously to deliver the product of their labors on a restricted time scale and to provide the most up-to­ date information on their respective topics. We are truly grateful for their indulgence.

• Calcium
• Coenzym
• DNA
• Lipid
• Oxidation
• Vitamin D
• gene expression
• metabolism

`The heterogeneity of topics...is very ambitious, and the result is, overall, successful because of the high quality of the individual contributors.'
American Scientist

`Well produced, well referenced and has a good index; it should become a standard reference work.'
Analyst

• King’s College London, University of London, London, UK

  Peter J. Quinn

• Department of Environmental and Occupational Health, and Department of Pharmacology, University of Pittsburgh, Pittsburgh, USA

  Valerian E. Kagan

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