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Handbook of Cancer Vaccines

  • Book
  • © 2004

Overview

Editors:
  1. Michael A. Morse

    1. Duke University Medical Center, Durham, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Timothy M. Clay

    1. Duke University Medical Center, Durham, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. H. Kim Lyerly

    1. Duke University Medical Center, Durham, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Cancer Drug Discovery and Development (CDD&D)

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Table of contents (37 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Basic Science of Tumor Antigens and Immune Activation

    1. Front Matter

      Pages 1-1
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    2. Biology of the Cancer Vaccine Immune Response

      • Michael A. Morse, Timothy M. Clay, H. Kim Lyerly
      Pages 3-10

    3. The Rational Design of T-Cell Epitopes With Enhanced Immunogenicity

      • John Fikes
      Pages 11-17

    4. Identification of Tumor Antigens Using Subtraction and Microarrays

      • Jiangchun Xu
      Pages 19-29

    5. Tumor Antigen Discovery With T Cells

      • Paul F. Robbins
      Pages 31-47

    6. Targeting Viral Antigens for the Treatment of Malignancies

      • Gretchen L. Eiben, Diane M. Da Silva, Steven C. Fausch, Amanda M. Krier, I. Caroline Le Poole, Megan E. Papineau et al.
      Pages 49-64

    7. Immune Defects in Cancer

      • Dmitry Gabrilovich, Vladimir Pisarev
      Pages 65-84

    8. Escape of Tumors From the Immune System

      • Gerard C. Blobe
      Pages 85-95

  3. General Vaccine and Immunotherapy Strategies

    1. Front Matter

      Pages 97-97
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    2. Immune Adjuvants

      • Jory R. Baldridge, Susan Hand Zimmermann, Sally P. Mossman
      Pages 99-114

    3. Heterologous Prime-Boost Vaccination in Tumor Immunotherapy

      • Michael J. Palmowski, Caroline Smith
      Pages 115-120

    4. Peptide-Based Vaccines

      • Carmen M. Berger, Keith L. Knutson, Lupe G. Salazar, PA-C Kathy Schiffman, Mary L. Disis
      Pages 121-135

    5. Antibody-Inducing Cancer Vaccines Against Cell-Surface Carbohydrate Antigens

      • Govind Ragupathi, John Gathuru, Philip O. Livingston
      Pages 137-155

    6. Anti-Idiotype Vaccines

      • Sunil K. Chatterjee, Malaya Bhattacharya-Chatterjee, Kenneth A. Foon
      Pages 157-173

    7. Pox Viral Vaccines

      • James L. Gulley, Philip M. Arlen, Jeffrey Schlom
      Pages 175-191

    8. Utility of Adenovirus-Based Vectors for Multiple Cancer Vaccine Approaches

      • Zachary Hartman, Andrea Amalfitano
      Pages 193-202

    9. Alphaviral-Based Strategies for the Immunotherapy of Cancer

      • Edward L. Nelson, Jonathan Smith
      Pages 203-224

    10. DNA Vaccines

      • Michael Bereta, Howard L. Kaufman
      Pages 225-248

    11. Whole-Tumor-Cell Vaccines

      • Timothy M. Clay, Paul J. Mosca, H. Kim Lyerly, Michael A. Morse
      Pages 249-251
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Keywords

About this book

An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.

Reviews

"This is an excellent resource for anyone interested in tumor immunotherapy. It is truly a comprehensive review of vaccination strategies for the treatment of cancer. The third section looks at the results of vaccine-based clinical trials for various malignancies. This section is an exceptional reference for oncologists. The chapters on melanoma are particularly helpful in sorting through the saga of vaccination for this deadly disease. The concluding section, important for clinical researchers, focuses on clinical trial design, the analysis of immune responses, and vaccine regulatory issues. " -Doody's Health Sciences Book Review Journal

"Highly recommended for medical schools and hospital libraries." - E-STREAMS

"...Comprehensive and authoritative...makes available to medical oncologists and immunologists a cutting-edge synthesis of the scientific rationale, preclinical data, and clinical results for the powerful new generation of vaccines now under development and treatment of a wide range of human cancers." - Tumori

Editors and Affiliations

  • Duke University Medical Center, Durham, USA

    Michael A. Morse, Timothy M. Clay, H. Kim Lyerly

Bibliographic Information

  • Book Title: Handbook of Cancer Vaccines

  • Editors: Michael A. Morse, Timothy M. Clay, H. Kim Lyerly

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1007/978-1-59259-680-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2004

  • Hardcover ISBN: 978-1-58829-209-4Published: 28 January 2004

  • Softcover ISBN: 978-1-4684-9818-9Published: 24 July 2012

  • eBook ISBN: 978-1-59259-680-5Published: 28 January 2004

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: XVIII, 592

  • Number of Illustrations: 39 b/w illustrations, 1 illustrations in colour

  • Topics: Oncology

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