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Fuel Homeostasis and the Nervous System

  • Book
  • © 1991

Overview

Editors:
  1. Mladen Vranic

    1. University of Toronto, Toronto, Canada

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  2. Suad Efendic

    1. Karolinska Hospital, Stockholm, Sweden

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    You can also search for this editor in PubMed   Google Scholar

  3. Charles H. Hollenberg

    1. Banting and Best Diabetes Centre, University of Toronto, Toronto, Canada

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 291)

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Table of contents (21 chapters)

  1. Front Matter

    Pages ii-x
    Download chapter PDF

  2. Methods to Study Fuel Homeostasis in the Brain

    1. The Metabolic Requirements of Functional Activity in the Human Brain: A Positron Emission Tomography Study

      • Marcus E. Raichle
      Pages 1-4

    2. High Resolution NMR Studies of Cerebral Glucose Metabolism in Rats and Humans

      • R. G. Shulman, D. L. Rothman, K. L. Behar, J. W. Prichard
      Pages 5-8

    3. Use of Peptide Probes to Study Brain Regulation of Glucose Metabolism

      • Marvin R. Brown
      Pages 9-19

  4. Peptide Signals in the Nervous System and Fuel Homeostasis

    1. Novel Peptides and Islet Function

      • Kazuhiko Tatemoto
      Pages 89-98

    2. Relationships Between the Hypothalamus and Adipose Tissue Mass

      • Daniel A. K. Roncari
      Pages 99-105

    3. Neural Control of Islet Function by Norepinephrine and Sympathetic Neuropeptides

      • Beth E. Dunning, Gerald J. Taborsky Jr.
      Pages 107-127

    4. Neuropeptides in the Regulation of Islet Hormone Secretion — Localization, Effects and Mode of Action

      • Bo Ahrén, Per-Olof Berggren, Patrik Rorsman, Claes-Göran Östenson, Suad Efendic
      Pages 129-142

    5. Proglucagon-Derived Peptides in the Neuroendocrine System

      • P. L. Baibaker, K. M. Stobie, J. N. Roberge, E. Y. T. Lui, D. J. Drucker
      Pages 143-159

    6. Effect of Stress on Glucoregulation in Physiology and Diabetes

      • M. Vranic, P. Miles, K. Rastogi, K. Yamatani, Z. Shi, L. Lickley et al.
      Pages 161-183

  5. Neural Responses to Abnormalities in Fuel Homeostasis

    1. Search for the Hypoglycemia Receptor Using the Local Irrigation Approach

      • Casey M. Donovan, Patricia Cane, Richard N. Bergman
      Pages 185-196

    2. Hypoglycemia, Gluconeogenesis and the Brain

      • A. D. Cherrington, R. T. Frizzell, D. W. Biggers, C. C. Connolly
      Pages 197-211

    3. Metabolism of Glucose in the Brain of IDDM Subjects

      • Valdemar Grill
      Pages 213-222

    4. Eating Disorders as Assessed by Cranial Computerized Tomography (CCT, dSPECT, PET)

      • Jürgen-Christian Krieg
      Pages 223-229

    5. Abnormal Brain Glucose Metabolism in Alzheimer’s Disease, as Measured by Positron Emission Tomography

      • Stanley I. Rapoport, Barry Horwitz, Cheryl L. Grady, James V. Haxby, Charles DeCarli, Mark B. Schapiro
      Pages 231-248

    6. A Correlation Between Gene Transcriptional Activity and Cerebral Glucose Metabolism in Alzheimer’s Disease-Affected Neocortex: Cause or Effect?

      • W. J. Lukiw, P. Handley, M. K. Sutherland, L. Wong, D. R. McLachlan
      Pages 249-256
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Keywords

About this book

This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm.

Editors and Affiliations

  • University of Toronto, Toronto, Canada

    Mladen Vranic

  • Karolinska Hospital, Stockholm, Sweden

    Suad Efendic

  • Banting and Best Diabetes Centre, University of Toronto, Toronto, Canada

    Charles H. Hollenberg

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