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Drugs, Lipid Metabolism, and Atherosclerosis

  • Book
  • © 1978

Overview

Editors:
  1. David Kritchevsky

    1. The Wistar Institute, Philadelphia, USA

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  2. Rodolfo Paoletti

    1. Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. William L. Holmes

    1. Division of Research, The Lankenau Hospital, Philadelphia, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 109)

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xi
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  2. Lipoproteins and Drugs

    1. Front Matter

      Pages 1-1
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    2. Lipoprotein Metabolism — New Insights from Cell Biology

      • Daniel Steinberg
      Pages 3-27

    3. Lipoprotein Metabolism in Man

      • G. Schlierf, P. Oster, D. Lang, H. Raetzer, B. Schellenberg, C. C. Heuck
      Pages 29-43

    4. Relative Atherogenicity of Different Plasma Lipoproteins

      • Donald B. Zilversmit
      Pages 45-59

    5. A New Approach to the Investigation of Drugs Affecting Lipoproteins

      • R. Paoletti, C. R. Sirtori, G. C. Ghiselli, R. Fumagalli
      Pages 61-76

    6. New Hypolipidemic Drugs

      • William L. Bencze
      Pages 77-95

  4. Drugs, Lipid Mobilization and Platelets

    1. Front Matter

      Pages 207-207
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    2. Mechanisms of Lipomobilization

      • Giuliana Fassina
      Pages 209-223

    3. Nicotinic Acid and Inhibition of Fat Mobilizing Lipolysis. Present Status of Effects on Lipid Metabolism

      • Lars A. Carlson
      Pages 225-238

    4. Drug Effects on Platelet Aggregation and Prostaglandin Formation

      • J. B. Smith, C. M. Ingerman, M. J. Silver
      Pages 239-251

    5. Drug Effects on Platelet Adherence to Collagen and Damaged Vessel Walls

      • M. A. Packham, J.-P. Cazenave, R. L. Kinlough-Rathbone, J. F. Mustard
      Pages 253-276

    6. Selected Animal Models for Systematic Antiatherosclerotic Drug Development

      • Charles E. Day, Paul E. Schurr, William A. Phillips
      Pages 277-283

  5. Cholesterol Metabolism in Man

    1. Front Matter

      Pages 285-285
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Keywords

About this book

This volume comprises the proceedings of the sixth International Symposium on Drugs Affecting Lipid Meta­ bolism. Since the first of these symposia in 1960 these triennial meetings have been devoted to the exploration of new ideas, new data and new concepts related to lipid metabolism and atherosclerosis. The sixth Meeting was particularly stimulating in this regard. The concept of the "protective" action of HDL was thoroughly explored within the framework of its molecular biology with data on its epidemiological as well as its in vitro mechan­ ism(s) of action being discussed. The action of drugs on arterial and HDL metabolism was also discussed as were newer aspects of platelet aggregation, especially as related to prostaglandins. New ground was also broken in discussions of lipid mobilization and mechan­ isms of hypocholesteremia. We are indebted to the many organizations who con­ tributed generously to the support of this meeting. Among the sponsors, the assistance of the Lorenzini Foundation was especially helpful. As in all meetings of this type, the hard work of the local organizing committee was instrumental in its success. We are grateful to Mrs. Caroline Hyatt and Mr. Ralph Hollerorth for their invaluable help in the secretariat. We are also deeply indebted to Miss Jane T. Kolimaga for her expert assistance in the preparation of this volume. David Kritchevsky Rodolfo Paoletti William L. Holmes vii Contents LIPOPROTEINS AND DRUGS Lipoprotein Metabolism - New Insights from Cell Biology. . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 D. Steinberg Lipoprotein Metabolism in Man. . . . . . . . . . . . . . . . . . . .

Editors and Affiliations

  • The Wistar Institute, Philadelphia, USA

    David Kritchevsky

  • Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

    Rodolfo Paoletti

  • Division of Research, The Lankenau Hospital, Philadelphia, USA

    William L. Holmes

Bibliographic Information

  • Book Title: Drugs, Lipid Metabolism, and Atherosclerosis

  • Editors: David Kritchevsky, Rodolfo Paoletti, William L. Holmes

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-0967-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1978

  • Softcover ISBN: 978-1-4684-0969-7Published: 25 November 2012

  • eBook ISBN: 978-1-4684-0967-3Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XI, 443

  • Topics: Pharmacology/Toxicology

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