Evolutionary Biology

1. Front Matter

   Pages i-xiv

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2. Darwinian Selection of Self-Replicating RNA Molecules

   • Christof K. Biebricher

   Pages 1-52

3. The Evolution of Enzyme Catalytic Efficiency and Adaptive Inference from Steady-State Kinetic Data

   • John G. Hall, Richard K. Koehn

   Pages 53-96

4. The Role of Single-Gene Mutations in the Evolution of Flowering Plants

   • Khidir W. Hilu

   Pages 97-128

5. Maintenance of Genetic Variation in Plant Populations

   • R. A. Ennos

   Pages 129-155

6. Evolutionary Genetics and the Genetic Control of Morphogenesis in Flowering Plants

   • Konrad Bachmann

   Pages 157-208

7. Phenotypic Evolution in Microfossils

   • R. A. Reyment

   Pages 209-254

8. Monocotyledon Evolution

   • Rolf Dahlgren, Finn N. Rasmussen

   Pages 255-395

9. Biochemical and Immunological Systematics of the Order Crocodilia

   • Llewellyn D. Densmore III

   Pages 397-465

10. The Establishment of Novel Mate-Recognition Systems in Introgressive Hybrid Drosophila Populations

    • Bruce Wallace, Milton W. Timm, Marina P. P. Strambi

    Pages 467-488

11. Back Matter

    Pages 489-499

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Sixteen volumes and one supplement have now appeared in the series known as Evolutionary Biology. The editors continue to seek critical re­ views, original papers, and commentaries on controversial topics. It is our aim to publish papers primarily of greater length and depth than those normally published by society journals and quarterlies. The editors make every attempt to solicit manuscripts on an international scale and to see that every facet of evolutionary biology-classical or modern-is cov­ ered. Manuscripts should be sent to anyone of the following: Max K. Hecht, Department of Biology, Queens College of the City University of New York, Flushing, New York 11367; Bruce Wallace, Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061; Ghillean T. Prance, New York Botanical Garden, Bronx, New York 10458. The Editors vii Contents 1. Darwinian Selection of Self-Replicating RNA Molecules 1 Christ(~r K. Biehricher Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Replication of Virus RNA in Vitro. . . . . . . . . . . . . . . . . . . . . . . . 2 Extracellular Darwinian Experiments. . . . . . . . . . . . . . . . . . . . . . 5 Characterization of the QI3 Replicase. . . . . . . . . . . . . . . . . . . . . . 9 Nonviral RNA Templates of QI3 Replicase. . . . . . . . . . . . . . . . . . II The Mechanism of RNA Replication . . . . . . . . . . . . . . . . . . . . . . 14 Initiation of Replication and Template Specificity . . . . . . . . . . . 14 Mechanism of Replica Chain Elongation. . . . . . . . . . . . . . . . . . 17 Termination of Replication. . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Replication of RNA Variants . . . . . . . . . . . . . . . . . . . . . . . . . . 21 The Quasispecies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 De NOl'O Synthesis of Self-Replicating RNA. . . . . . . . . . . . . . . . . 27 The Mechanism of Selection . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 Selection in the Exponential Growth Phase. . . . . . . . . . . . . . . . 32 Selection in the Linear Growth Phase. . . . . . . . . . . . . . . . . . . . 35 Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41 Appendix I. Replication. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 Appendix II. The Quasispecies. . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Appendix III. Selection under Various Conditions . . . . . . . . . . . . 44 References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

• Charles Darwin
• Darwin
• Wallace
• biology
• evolution
• evolutionary biology

• Queens College, City University of New York, Flushing, USA

  Max K. Hecht

• Virginia Polytechnic Institute and State University, Blacksburg, USA

  Bruce Wallace

• New York Botanical Garden, Bronx, USA

  Ghillean T. Prance

Policies and ethics