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Alcohol Use Disorders and the Lung

A Clinical and Pathophysiological Approach

  • Book
  • © 2014

Overview

Editors:
  1. David M. Guidot

    1. Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine and the Atlanta VA Medical Center, Atlanta, USA

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  2. Ashish J. Mehta

    1. Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine and the Atlanta VA Medical Center, Decatur, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive review of the pathophysiology of alcohol-related lung disorders
  • Presents evolving therapeutic options
  • Excellent resource for a wide range of clinicians caring for individuals affected by alcohol use disorders?

Part of the book series: Respiratory Medicine (RM)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-x
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  3. The Pathophysiology of the “Alcoholic Lung”

    1. Front Matter

      Pages 47-47
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    2. Alcohol, the Upper Airway, and Mucociliary Dysfunction in the Conducting Airways

      • Todd A. Wyatt, Joseph H. Sisson
      Pages 49-62

    3. Alcohol and the Alveolar Macrophage

      • Samantha M. Yeligar, Yan Liang, Lou Ann S. Brown
      Pages 63-81

    4. Alcohol and the Alveolar Epithelium

      • Samuel A. Molina, Michael Koval
      Pages 83-101

    5. Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol Depletion

      • Samantha M. Yeligar, Yan Liang, Lou Ann S. Brown
      Pages 103-114

    6. Alcohol and the Adaptive Immune Response in the Airway: Dendritic Cell and Lymphocyte Impairments

      • Kevin L. Legge, Thomas J. Waldschmidt
      Pages 115-132

    7. Alcohol Impairment of Granulocyte Function During Lung Infection

      • Gregory J. Bagby, Kyle I. Happel, J. Nicholas Melvan
      Pages 133-153

    8. Disruption in the Dynamic Balance Between Transforming Growth Factor-β and Granulocyte/Macrophage Colony-Stimulating Factor Signaling Within the Alveolar Space of the Alcoholic Lung: Impact on Epithelial and Macrophage Function

      • David M. Guidot, Ashish J. Mehta
      Pages 155-171

    9. Alcohol-Mediated Zinc Deficiency Within the Alveolar Space: A Potential Fundamental Mechanism Underlying Oxidative Stress and Cellular Dysfunction in the Alcoholic Lung

      • Ashish J. Mehta, David M. Guidot
      Pages 173-184

  4. Special Circumstances

    1. Front Matter

      Pages 185-185
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    2. The Impact of Alcohol Abuse on Multiple Organ Dysfunction in the Surgical Patient

      • Katharina Chalk, Claudia Spies
      Pages 187-210

    3. Alcohol and HIV: Experimental and Clinical Evidence of Combined Impact on the Lung

      • Sushma K. Cribbs, David Rimland
      Pages 211-229

    4. Maternal Alcohol Use and the Neonate

      • Theresa W. Gauthier, Danielle Giliberti, Sowmya S. Mohan, Juna Konomi, Lou Ann S. Brown
      Pages 231-245
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Keywords

About this book

Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.

Editors and Affiliations

  • Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine and the Atlanta VA Medical Center, Atlanta, USA

    David M. Guidot

  • Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine and the Atlanta VA Medical Center, Decatur, USA

    Ashish J. Mehta

Bibliographic Information

  • Book Title: Alcohol Use Disorders and the Lung

  • Book Subtitle: A Clinical and Pathophysiological Approach

  • Editors: David M. Guidot, Ashish J. Mehta

  • Series Title: Respiratory Medicine

  • DOI: https://doi.org/10.1007/978-1-4614-8833-0

  • Publisher: Humana New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-4614-8832-3Published: 20 October 2013

  • Softcover ISBN: 978-1-4939-4500-9Published: 23 August 2016

  • eBook ISBN: 978-1-4614-8833-0Published: 19 October 2013

  • Series ISSN: 2197-7372

  • Series E-ISSN: 2197-7380

  • Edition Number: 1

  • Number of Pages: X, 252

  • Number of Illustrations: 11 b/w illustrations, 15 illustrations in colour

  • Topics: Pneumology/Respiratory System, Intensive / Critical Care Medicine, Psychiatry, Internal Medicine

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