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Prostate Cancer

Biochemistry, Molecular Biology and Genetics

  • Book
  • © 2013

Overview

Editors:
  1. Donald J. Tindall

    1. , Depts of Urology, and, Mayo Clinic College of Medicine, Rochester, USA

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  • Gives the reader a comprehensive conceptual framework of the cellular mechanism that are critical for the initiation and progression of prostate cancer
  • Geared toward basic scientists, instead of largely clinically oriented
  • Includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells, and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer

Part of the book series: Protein Reviews (PRON, volume 16)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-xii
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  2. Cell Biology

    1. Front Matter

      Pages 1-1
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    2. Stem Cells in the Normal and Malignant Prostate

      • Norman J. Maitland
      Pages 3-41

    3. Role of Reactive Stroma in Prostate Cancer

      • Rebeca San Martin, David R. Rowley
      Pages 43-63

    4. The Role of Cholesterol in Prostate Cancer

      • Keith R. Solomon, Kristine Pelton, Michael R. Freeman
      Pages 65-83

  3. Genetics

    1. Front Matter

      Pages 85-85
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    2. PTEN in Prostate Cancer

      • Marcus A. Ruscetti, Hong Wu
      Pages 87-137

    3. ETS Fusion Genes in Prostate Cancer

      • J. Chad Brenner, Arul M. Chinnaiyan, Scott A. Tomlins
      Pages 139-183

  4. Cell Signaling

    1. Front Matter

      Pages 185-185
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    2. Signaling Mechanisms of Vav3, a Guanine Nucleotide Exchange Factor and Androgen Receptor Coactivator, in Physiology and Prostate Cancer Progression

      • Leah S. Lyons, Kerry L. Burnstein
      Pages 187-205

    3. Transforming Growth Factor-Beta in Prostate Cancer

      • David Danielpour
      Pages 207-242

    4. The p38 MAPK Pathway in Prostate Cancer

      • Daniel Djakiew
      Pages 243-255

    5. NF-kappaB2/p52 in Prostate Cancer

      • Nagalakshmi Nadiminty, Ramakumar Tummala, Yezi Zhu, Allen C. Gao
      Pages 257-273

    6. The Functional Role of DAB2IP, a Homeostatic Factor, in Prostate Cancer

      • Eun-Jin Yun, Kaijie Wu, Yuh-Shyan Tsai, Daxing Xie, Jer-Tsong Hsieh
      Pages 275-293

    7. Tyrosine Kinases in Prostate Cancer

      • Yun Qiu, Dhanraj Deshmukh
      Pages 295-322

    8. Human Prostatic Acid Phosphatase in Prostate Carcinogenesis

      • Sakthivel Muniyan, Yu-Wei Chou, Shou-Qiang Ou-Yang, Ming-Fong Lin
      Pages 323-348

  5. Hormonal

    1. Front Matter

      Pages 349-349
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    2. Truncated Androgen Receptor Splice Variants in Prostate Cancer

      • Peter E. Lonergan, Donald J. Tindall
      Pages 351-382

    3. Biology and Clinical Relevance of Estrogen Receptors in Prostate Cancer

      • Shuk-Mei Ho, Pheruza Tarapore, Ming-Tsung Lee, Yuet-Kin Leung
      Pages 383-419

    4. Vitamin D and Prostate Cancer

      • Jung-Sun Kim, Justin M. Roberts, Nancy L. Weigel
      Pages 421-442
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Keywords

About this book

Prostate Cancer provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. It includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer.

Editors and Affiliations

  • , Depts of Urology, and, Mayo Clinic College of Medicine, Rochester, USA

    Donald J. Tindall

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