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  • Book
  • © 2012

Engineering Biomaterials for Regenerative Medicine

Novel Technologies for Clinical Applications

  • Details strategies for addressing specific disease states with tissue engineering and regenerative medicine
  • Discusses the latest generation of regenerative biomaterials
  • Allows biomaterials researchers to understand the clinical targets and requirements for regenerative medicine
  • Provides a multi-disciplinary approach with contributions from departments of chemical engineering, polymer science, bioengineering, and medicine
  • Edited by an M.D./Ph.D. with an integrated perspective into both research and clinical issues
  • Includes supplementary material: sn.pub/extras

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-x
  2. Cellular Recruitment and Delivery

    1. Front Matter

      Pages 1-1
    2. Matrix Stiffness: A Regulator of Cellular Behavior and Tissue Formation

      • Brooke N. Mason, Joseph P. Califano, Cynthia A. Reinhart-King
      Pages 19-37
  3. Oxygen Delivery

    1. Front Matter

      Pages 39-39
    2. Oxygen Supply for Tissue Engineering

      • Whitney L. Stoppel, Susan C. Roberts
      Pages 41-86
  4. Tuning of Mechanical Properties

    1. Front Matter

      Pages 87-87
    2. Adhesion Behavior of Soft Materials

      • Santanu Kundu, Edwin P. Chan
      Pages 89-125
    3. PLA–PEO–PLA Hydrogels and Their Mechanical Properties

      • Gregory N. Tew, Surita R. Bhatia
      Pages 127-140
  5. Control of Inflammation and Host Response

    1. Front Matter

      Pages 141-141
    2. Host Response to Biomaterials

      • Anjelica L. Gonzalez-Simon, Omolola Eniola-Adefeso
      Pages 143-159
    3. Modulation of the Wound Healing Response Through Oxidation Active Materials

      • Paritosh P. Wattamwar, Thomas D. Dziubla
      Pages 161-192
  6. Biologically Inspired Materials for Tissue Regeneration

    1. Front Matter

      Pages 193-193
    2. Gecko-Inspired Tape-Based Adhesives

      • Woo Kyung Cho, Maria José Maio Nunes Pereira, Nora Lang, Kyungheon Lee, Shwetha Mureli, Andreas Zumbuehl et al.
      Pages 195-223
    3. Heparin-Functionalized Materials in Tissue Engineering Applications

      • Christopher McGann, Kristi Kiick
      Pages 225-250
  7. Clinical Applications of Tissue Regeneration

    1. Front Matter

      Pages 251-251
    2. Tissue Engineering Strategies for Vocal Fold Repair and Regeneration

      • Alexandra J. E. Farran, Zhixiang Tong, Robert L. Witt, Xinqiao Jia
      Pages 253-284
    3. Nonviral Gene Delivery for Applications in Regenerative Medicine

      • Kory Blocker, Millicent Sullivan
      Pages 285-319

About this book

Regeneration of tissues and organs remains one of the great  challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement.   Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress  is made possible by advances in materials science, polymer chemistry, and molecular biology.  This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice.  The latest methods for regulating the biological and chemical composition of biomaterials are described, together with  techniques for modulating mechanical properties of engineered constructs.  Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility.  The book culminates in a discussion of the clinical applications of regenerative medicine.

By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine  examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic.  The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and  will also enable physicians to understand novel biomaterials that are emerging in the clinic.  This integrated approach also gives engineering students a sense of the excitement and relevance of materials science  in the development of novel therapeutic strategies.

Editors and Affiliations

  • , School of Engineering and Applied Scienc, Harvard University, Cambridge, USA

    Sujata K. Bhatia

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access