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  • © 2012

Notch Signaling in Embryology and Cancer

  • Comprehensive in scope, covers an overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology
  • Topics are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer
  • Brings the diverse scientific and clinical fields together in one definitive and up-to-date volume

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 727)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xxi
  2. The Molecular Basis of Notch Signaling: A Brief Overview

    • Sang-Mo Kwon, Cantas Alev, Sang-Hun Lee, Takayuki Asahara
    Pages 1-14
  3. The Role of Adams in Notch Signaling

    • Arjan J. Groot, Marc A. Vooijs
    Pages 15-36
  4. Notch Signaling and Development of the Hematopoietic System

    • Ashley R. Sandy, Morgan Jones, Ivan Maillard
    Pages 71-88
  5. Notch Signaling in Lung Development and Disease

    • Keli Xu, Nadeem Moghal, Sean E. Egan
    Pages 89-98
  6. The Role of Notch Signaling in Kidney Development and Disease

    • Hila Barak, Kameswaran Surendran, Scott C. Boyle
    Pages 99-113
  7. Notch Signaling and the Developing Skeleton

    • Timothy J. Mead, Katherine E. Yutzey
    Pages 114-130
  8. Notch Signaling and the Developing Skin Epidermis

    • Daniela Massi, John Panelos
    Pages 131-141
  9. Notch Signaling and the Developing Hair Follicle

    • Geneviève Aubin-Houzelstein
    Pages 142-160
  10. Notch Signaling and the Developing Inner Ear

    • Junko Murata, Katsuhisa Ikeda, Hideyuki Okano
    Pages 161-173
  11. Notch Signaling in Cancer Stem Cells

    • Jialiang Wang, Bruce A. Sullenger, Jeremy N. Rich
    Pages 174-185
  12. Notch Signaling Pathway and Cancer Metastasis

    • Yi-Yang Hu, Min-hua Zheng, Rui Zhang, Ying-Min Liang, Hua Han
    Pages 186-198
  13. Notch, Apoptosis and Cancer

    • Thao P. Dang
    Pages 199-209
  14. Notch Signaling and Breast Cancer

    • Michael Reedijk
    Pages 241-257
  15. Notch Signaling and Malignant Melanoma

    • Cornelia S. L. Müller
    Pages 258-264

About this book

The goal of this volume is to comprehensively cover a highly readable overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer. Experts in the field as well as scientists and health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for every clinician or scientist interested in the role of Notch signalling in embryology and cancer. We hope that this volume will be adopted as the standard text in this area of science and will stimulate new interest in the role of Notch signalling for embryology and cancer. We further hope that this compendium will serve as both a source for current researchers and a guide to stimulate and assist those in related disciplines to enter this exciting field of research.

Editors and Affiliations

  • Department of Dermatology, The Saarland University Hospital, Homburg, Germany

    Jörg Reichrath

  • Department of Internal Medicine I, The Saarland University Hospital, Homburg, Germany

    Sandra Reichrath

About the editors

JÖRG REICHRATH is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Hospital in Homburg/Saar, Germany. Main research interests include photobiology, dermato-endocrinology and dermato-oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), the German Dermatologic Cooperative Oncology Group (DeCOG), and the European Society of Dermatological Research (ESDR). He has been awarded numerous prices including the Arnold-Rikli-price 2006. Jörg Reichrath received his academic degrees (Dr. med., venia legendi) from the Saarland University, Germany.

SANDRA REICHRATH is working as a scientist at the Clinic for Internal Medicine of the Saarland University Hospital in Homburg/Saar, Germany. Main research interests include Notch signalling in glioblastoma and skin tumors. She received her academic degrees from the Faculty of Biology of the Albert-Ludwig-University, Freiburg, Germany.

Bibliographic Information

  • Book Title: Notch Signaling in Embryology and Cancer

  • Editors: Jörg Reichrath, Sandra Reichrath

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4614-0899-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • eBook ISBN: 978-1-4614-0899-4Published: 07 March 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXII, 322

  • Number of Illustrations: 61 b/w illustrations, 8 illustrations in colour

  • Topics: Cancer Research, Cell Biology

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access