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Advances in Cancer Stem Cell Biology

  • Book
  • © 2012

Overview

Editors:
  1. Roberto Scatena

    1. , Department of Laboratory Medicine, Catholic University, Rome, Italy

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  2. Alvaro Mordente

    1. School of Medicine, Institute of Biochemistry, Catholic University, Rome, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Bruno Giardina

    1. , Department of Laboratory Medicine, Catholic University, Rome, Italy

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  • Identifies a molecular phenotype for modified stem cells

  • Looks into the first challenge of molecular oncology

  • Gives insight into pathogenetic mechanisms at the basis of cancer stem cells

  • Includes supplementary material: sn.pub/extras

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
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  2. Cancer Stem Cells: A Revisitation of the “Anaplasia” Concept

    • Roberto Scatena
    Pages 1-16

  3. Stem Cells and Cancer Stem Cells: New Insights

    • Toru Kondo
    Pages 17-31

  4. Molecular Biology of Cancer Stem Cells

    • Oswaldo Keith Okamoto
    Pages 33-43

  5. Biomarkers of Cancer Stem Cells

    • Jun Dou, Ning Gu
    Pages 45-67

  6. Cancer Stem Cells and the Microenvironment

    • Alfonso Colombatti, Carla Danussi, Eliana Pivetta, Paola Spessotto
    Pages 69-84

  7. Leukemia Stem Cells

    • Steven W. Lane, David A. Williams
    Pages 85-103

  8. Cancer Stem Cells and the Central Nervous System

    • Serdar Korur, Maria Maddalena Lino, Adrian Merlo
    Pages 105-121

  9. Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects

    • Akio Soeda, Mark E. Shaffrey, Deric M. Park
    Pages 123-140

  10. Breast Cancer Stem Cells

    • Nuria Rodríguez Salas, Enrique González González, Carlos Gamallo Amat
    Pages 141-154

  11. Colon Cancer Stem Cells

    • Ugo Testa
    Pages 155-179

  12. Liver Tumor-Initiating Cells/Cancer Stem Cells: Past Studies, Current Status, and Future Perspectives

    • Kwan Ho Tang, Stephanie Ma, Xin-Yuan Guan
    Pages 181-196

  13. Pancreatic Cancer Stem Cells

    • Erica N. Proctor, Diane M. Simeone
    Pages 197-209

  14. Cancer Stem Cells and Renal Carcinoma

    • Benedetta Bussolati, Giovanni Camussi
    Pages 211-220

  15. Cancer Stem Cells: Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers

    • Patrizia Bottoni, Bruno Giardina, Roberto Scatena
    Pages 221-238

  16. Cancer Stem Cells: An Innovative Therapeutic Approach

    • Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà, Bruno Giardina
    Pages 239-266

  17. Cancer Stem Cell and ATP-Binding Cassette: Which Role in Chemoresistance?

    • Andrea Silvestrini, Elisabetta Meucci, Giuseppe Ettore Martorana, Bruno Giardina, Alvaro Mordente
    Pages 267-288

  18. Stem Cells and Cancer Stem Cells: Biological and Clinical Interrelationships

    • Cinzia Bagalà, Carlo Barone
    Pages 289-300

  19. Immunomodulatory Functions of Cancer Stem Cells

    • Tobias Schatton, Jennifer Y. Lin, Markus H. Frank
    Pages 301-332

  20. Back Matter

    Pages 333-343
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Keywords

About this book

In recent years, cancer stem cells have been recognized as important component in carcinogenesis and they seem to form the basis of many (if not all) tumor types. Cancer stem cells or "cancer cell like stem cells" have been isolated from various cancers of different origin (blood, breast, brain, skin, head and neck, thyroid, cervix, lung, retina, colon, pancreas and so on). Cancer stem cells - rare cells with indefinite proliferative potential that drive the formation and growth of tumours- seem to show intriguing relationships with physiological stem cells. Specifically, these cancer cells show significant similarities in the mechanisms that regulate self-renewal of normal stem cells. Moreover, tumour cells might directly arise from normal stem cells. Further, the cellular biology of cancer stem cells show a lot of similarities with normal stem cells.

Editors and Affiliations

  • , Department of Laboratory Medicine, Catholic University, Rome, Italy

    Roberto Scatena, Bruno Giardina

  • School of Medicine, Institute of Biochemistry, Catholic University, Rome, Italy

    Alvaro Mordente

Bibliographic Information

  • Book Title: Advances in Cancer Stem Cell Biology

  • Editors: Roberto Scatena, Alvaro Mordente, Bruno Giardina

  • DOI: https://doi.org/10.1007/978-1-4614-0809-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-0808-6Published: 05 October 2011

  • Softcover ISBN: 978-1-4939-0059-6Published: 08 December 2014

  • eBook ISBN: 978-1-4614-0809-3Published: 06 October 2011

  • Edition Number: 1

  • Number of Pages: XII, 343

  • Topics: Cancer Research, Pharmacology/Toxicology

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