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Diffuse Low-Grade Gliomas in Adults

Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies

  • Book
  • © 2013

Overview

Editors:
  1. Hugues Duffau

    1. , INSERM U1051, Institute for Neurosciences of Montpelli, Montpellier, France

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  • Focus on diffuse low-grade gliomas in adults Consideration of both DLGG and its interaction with the brain (cerebral plasticity)
  • Covers both oncological and functional perspectives on DLGGs in adults
  • Discussion of individualized management

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Introduction: From the Inhibition of Dogmas to the Concept of Personalized Management in Diffuse Low-Grade Gliomas

    • Hugues Duffau
    Pages 1-5

  3. Epidemiology and Classification

    1. Front Matter

      Pages 7-7
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    2. Epidemiology of Diffuse Low-Grade Gliomas

      • Luc Bauchet
      Pages 9-30

    3. Histological Classification

      • Valérie Rigau
      Pages 31-44

    4. Is Gliomatosis Cerebri a Diffuse Low-Grade Glioma?

      • Catherine Godfraind
      Pages 45-59

    5. Contribution of Molecular Biology to the Classification of Low-Grade Diffuse Glioma

      • Hiroko Ohgaki
      Pages 61-72

  4. Basic Science and Experimental Research in DLGG

    1. Front Matter

      Pages 73-73
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    2. Cellular Origin of Grade II Gliomas

      • Pierre-Olivier Guichet, Jean-Philippe Hugnot
      Pages 75-89

    3. Deciphering the Molecular and Cellular Basis for Dissemination of Diffuse Low-Grade Gliomas

      • Zahra Hassani, Jean-Philippe Hugnot
      Pages 91-98

    4. The Molecular Biology of Diffuse Low-Grade Gliomas

      • Nicholas F. Marko, Robert J. Weil
      Pages 99-115

    5. Proteomic Studies in Low-Grade Gliomas: What Have They Informed About Pathophysiology?

      • A. M. J. Gerth, R. F. Deighton, J. McCulloch, Ian R. Whittle
      Pages 117-136

    6. Human Low-Grade Glioma Cultures

      • Daniela Cesselli, Antonio Paolo Beltrami, Anja Pucer, Evgenia Bourkoula, Tamara Ius, Marco Vindigni et al.
      Pages 137-163

    7. Animal Models for Low-Grade Gliomas

      • Rolf Bjerkvig, Sébastien Bougnaud, Simone P. Niclou
      Pages 165-175

  5. Clinical Aspects and Diagnostic Imaging

    1. Front Matter

      Pages 177-177
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    2. Clinical Presentation in Diffuse Low-Grade Gliomas

      • Juan Torres-Reveron, Joseph M. Piepmeier, Kevin P. Becker
      Pages 179-188

    3. Epilepsy in Diffuse Low-Grade Gliomas

      • Anja Smits
      Pages 189-203

    4. Quality of Life in Low-Grade Gliomas

      • Martin J. B. Taphoorn
      Pages 205-217

    5. Metabolic-Oncological MR Imaging of Diffuse Low-Grade Glioma: A Dynamic Approach

      • Rémy Guillevin
      Pages 219-234

    6. Positron Emission Tomography in Diffuse Low-Grade Gliomas

      • Karl-Josef Langen, Frank Willi Floeth, Michael Sabel, Norbert Galldiks
      Pages 235-248
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Keywords

About this book

This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Editors and Affiliations

  • , INSERM U1051, Institute for Neurosciences of Montpelli, Montpellier, France

    Hugues Duffau

Bibliographic Information

  • Book Title: Diffuse Low-Grade Gliomas in Adults

  • Book Subtitle: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies

  • Editors: Hugues Duffau

  • DOI: https://doi.org/10.1007/978-1-4471-2213-5

  • Publisher: Springer London

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag London 2013

  • eBook ISBN: 978-1-4471-2213-5Published: 19 March 2013

  • Edition Number: 1

  • Number of Pages: XVII, 502

  • Number of Illustrations: 20 b/w illustrations, 53 illustrations in colour

  • Topics: Oncology, Neurology, Neuroradiology

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