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  • © 2011

Molecular Pathology of Liver Diseases

  • One-stop reference for comprehending the molecular mechanisms of hepatic pathobiology.
  • Unique format, readability and information.
  • Visual approach includes an abundance of tables and diagrams.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Molecular Pathology Library (MPLB, volume 5)

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Table of contents (63 chapters)

  1. Front Matter

    Pages i-xxiii
  2. Liver Cells and Functions

    1. Front Matter

      Pages 1-1
    2. Gross and Cellular Anatomy of the Liver

      • Allan Tsung, David A. Geller
      Pages 3-6
    3. Liver Zonation

      • Sabine Colnot, Christine Perret
      Pages 7-16
    4. Hepatocytes

      • Alejandro Soto-Gutierrez, Nalu Navarro-Alvarez, Naoya Kobayashi
      Pages 17-26
    5. Biliary Epithelial Cells

      • Yoshiaki Mizuguchi, Susan Specht, Kumiko Isse, John G. Lunz III, Anthony J. Demetris
      Pages 27-51
    6. Stellate Cells

      • Chandrashekhar R. Gandhi
      Pages 53-79
    7. Kupffer Cells

      • Chandrashekhar R. Gandhi
      Pages 81-95
    8. Sinusoidal Endothelial Cells

      • Donna Beer Stolz
      Pages 97-107
    9. Hepatic Carbohydrate Metabolism

      • Dirk Raddatz, Giuliano Ramadori
      Pages 109-123
    10. Hepatic Protein Metabolism

      • Wouter H. Lamers, Theodorus B. M. Hakvoort, Eleonore S. Köhler
      Pages 125-132
    11. Hepatic Lipid Metabolism

      • Jiansheng Huang, Jayme Borensztajn, Janardan K. Reddy
      Pages 133-146
    12. Detoxification Functions of the Liver

      • Udayan Apte, Partha Krishnamurthy
      Pages 147-163
    13. Bile Acid Metabolism

      • John Y. L. Chiang
      Pages 165-179
  3. Molecular Basis of Liver Development, Growth, and Senescence

    1. Front Matter

      Pages 181-181
    2. Liver Development

      • Klaus H. Kaestner
      Pages 183-191
    3. Bile Duct Development and Biliary Differentiation

      • Frederic P. Lemaigre
      Pages 213-224
    4. Hepatic Progenitors in Development and Transplantation

      • David A. Shafritz, Michael Oertel, Mariana D. Dabeva
      Pages 225-241
    5. Adult Liver Stem Cells

      • D. Hunter Best, William B. Coleman
      Pages 243-260

About this book

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Editors and Affiliations

  • School of Medicine, Dept. Pathology, University of Pittsburgh, Pittsburgh, USA

    Satdarshan P. S. Monga

About the editor

Satdarshan (Paul) Singh Monga, M.D. is Director: the Division of Experimental Pathology and Associate Professor of Pathology and Medicine, University of Pittsburgh, Pittsburgh, PA

Bibliographic Information

  • Book Title: Molecular Pathology of Liver Diseases

  • Editors: Satdarshan P. S. Monga

  • Series Title: Molecular Pathology Library

  • DOI: https://doi.org/10.1007/978-1-4419-7107-4

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-7106-7Published: 17 December 2010

  • Softcover ISBN: 978-1-4899-7782-3Published: 23 August 2016

  • eBook ISBN: 978-1-4419-7107-4Published: 14 December 2010

  • Series ISSN: 1935-987X

  • Series E-ISSN: 1935-9888

  • Edition Number: 1

  • Number of Pages: XXIII, 931

  • Number of Illustrations: 64 b/w illustrations, 448 illustrations in colour

  • Topics: Pathology, Molecular Medicine

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 299.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access