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Cytoskeleton of the Nervous System

  • Book
  • © 2011

Overview

Editors:
  1. Ralph A. Nixon

    1. Psychiatric Research, Nathan S. Kline Institute for, Orangeburg, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Aidong Yuan

    1. Psychiatric Research, Nathan S. Kline Institute for, Orangeburg, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Describes cytoskeleton in axonal development and pathology, microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein Focuses on functional significance of neuronal cytoskeleton in axonal transport Encourages further development of unifying principles, stimulates new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 3)

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Central Axonal Development and Pathology in Early Life

    • Robin L. Haynes, Hannah C. Kinney
    Pages 1-53

  3. Microtubules in the Nervous System

    • Nobuyuki Fukushima
    Pages 55-71

  4. Tau Phosphorylation

    • Jesús Avila, Félix Hernández
    Pages 73-82

  5. Tau Pathology

    • Nicolas Sergeant, Luc Buée
    Pages 83-132

  6. Tauopathy and Brain Aging

    • Akihiko Takashima
    Pages 133-150

  7. Microtubule-Associated Protein 4

    • Kiyotaka Tokuraku, Kazuyuki Matsushima, Hiroyuki Nakagawa, Susumu Kotani
    Pages 151-165

  8. Structure of Neural Intermediate Filaments

    • David A.D. Parry
    Pages 167-188

  9. Alpha-Internexin: The Fourth Subunit of Neurofilaments in the Mature CNS

    • Aidong Yuan, Ralph A. Nixon
    Pages 189-199

  10. Peripherin Pathology

    • Jesse R. McLean, Janice Robertson
    Pages 201-224

  11. Neurofilament Cross-Bridge – A Structure Associated Specifically with the Neurofilament Among the Intermediate Filament Family

    • Takahiro Gotow
    Pages 225-247

  12. Neurofilament Transport

    • Andrew J. Grierson, Christopher C.J. Miller
    Pages 249-260

  13. Knockout Models of Neurofilament Proteins

    • Rodolphe Perrot, Jean-Pierre Julien
    Pages 261-277

  14. Neurofilaments and Radial Growth: Deconstruction of a Hypothesis Through the Construction of Gene Targeted Mice

    • Michael L. Garcia, Devin M. Barry
    Pages 279-295

  15. Deregulation of Cytoskeletal Protein Phosphorylation and Neurodegeneration

    • Jyotshnabala Kanungo, Ya-li Zheng, Parvathi Rudrabhatla, Niranjana D. Amin, Bibhutibhushan Mishra, Harish C. Pant
    Pages 297-324

  16. Neurofilaments in Aged Animals

    • Shin-ichi Hisanaga, Takahiro Sasaki, Atsuko Uchida
    Pages 325-345

  17. Neurofilament Changes in Multiple Sclerosis

    • Elizabeth Gray, Alastair Wilkins
    Pages 347-377

  18. Intermediate Filament Interactions in Neurons

    • Kevin G. Young, Rashmi Kothary
    Pages 379-410

  19. Tropomyosins in Neuronal Morphogenesis and Development

    • Nikki Margarita Curthoys, Peter William Gunning, Thomas Fath
    Pages 411-445

  20. The Driving Machinery for Growth Cone Navigation

    • Takuro Tojima, Hiroyuki Kamiguchi
    Pages 447-454
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About this book

This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.

Editors and Affiliations

  • Psychiatric Research, Nathan S. Kline Institute for, Orangeburg, USA

    Ralph A. Nixon, Aidong Yuan

About the editors

Ralph A. Nixon is the Director of Silberstein Institute and Center of Excellence on Brain Aging; a Professor of Psychiatry and Cell Biology at NYU Langone Medical Center; the Director of Research and The Center for Dementia Research at Nathan S. Kline Institute for Psychiatric Research. Aidong (David) Yuan is the Research Project Manager at the Center for Dementia Research, Nathan S. Kline Institute; a Research Assistant Professor of Psychiatry at New York University Langone Medical Center and New York University School of Medicine.

Bibliographic Information

  • Book Title: Cytoskeleton of the Nervous System

  • Editors: Ralph A. Nixon, Aidong Yuan

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-1-4419-6787-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-4419-6786-2Published: 14 February 2011

  • Softcover ISBN: 978-1-4939-5142-0Published: 23 August 2016

  • eBook ISBN: 978-1-4419-6787-9Published: 04 February 2011

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: XV, 774

  • Topics: Neurosciences

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