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  • © 2010

Gene-Based Therapies for Cancer

Editors:

  • In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers
  • Translational gene therapy approaches are emphasized
  • Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials
  • This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Cancer Research (CUCR)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiv
  2. RNAi: A New Paradigm in Cancer Gene Therapy

    • Edna M. Mora, Selanere L. Mangala, Gabriel Lopez-Berestein, Anil K. Sood
    Pages 1-15
  3. Gene-Based Therapy for Cancer: Brain Tumors

    • Hong Jiang, Juan Fueyo
    Pages 17-32
  4. Gene Therapy of Prostate Cancer

    • Svend O. Freytag, Hans Stricker, Benjamin Movsas, Mohamed Elshaikh, Ibrahim Aref, Kenneth Barton et al.
    Pages 33-49
  5. siRNA Versus shRNA for Personalized Cancer Therapy: Mechanisms and Applications

    • John S. Vorhies, Donald D. Rao, Neil Senzer, John Nemunaitis
    Pages 51-62
  6. Tumor Suppressor Gene Therapy

    • Jack A. Roth, John Nemunaitis, Lin Ji, Rajagopal Ramesh
    Pages 63-78
  7. Gene Therapy for Malignant Pleural Mesothelioma

    • Edmund K. Moon, Sunil Singhal, Andrew R. Haas, Daniel H. Sterman, Steven M. Albelda
    Pages 95-111
  8. Mesenchymal Stem/Stromal Cells as Cellular Vehicles for Tumor Targeting

    • Frank Marini, Matus Studeny, Jennifer Dembinski, Keri L. Watson, Shannon Kidd, Erika Spaeth et al.
    Pages 113-139
  9. Retargeting Adenovirus for Cancer Gene Therapy

    • Erin E. Thacker, David T. Curiel
    Pages 141-153
  10. Lentiviruses: Vectors for Cancer Gene Therapy

    • Yuan Lin, Amar Desai, Stanton L. Gerson
    Pages 155-179
  11. Interleukin-24 Gene Therapy for Melanoma

    • Nancy Poindexter, Rajagopal Ramesh, Suhendan Ekmekcioglu, Julie Ellerhorst, Kevin Kim, Elizabeth A. Grimm
    Pages 181-202
  12. Herpes Simplex Virus 1 for Cancer Therapy

    • Richard L. Price, Balveen Kaur, E. Antonio Chiocca
    Pages 203-230
  13. Gene Therapy for Sarcoma

    • Keila E. Torres, Raphael E. Pollock
    Pages 251-268
  14. Back Matter

    Pages 269-275

About this book

Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.

Editors and Affiliations

  • M.D.Anderson Cancer Center, Dept. Thoracic & Cardiovascular Surgery, University of Texas, Houston, USA

    Jack A. Roth

Bibliographic Information

  • Book Title: Gene-Based Therapies for Cancer

  • Editors: Jack A. Roth

  • Series Title: Current Cancer Research

  • DOI: https://doi.org/10.1007/978-1-4419-6102-0

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-4419-6101-3Published: 04 August 2010

  • Softcover ISBN: 978-1-4614-2634-9Published: 13 October 2012

  • eBook ISBN: 978-1-4419-6102-0Published: 28 July 2010

  • Series ISSN: 2199-2584

  • Series E-ISSN: 2199-2592

  • Edition Number: 1

  • Number of Pages: XIV, 278

  • Topics: Cancer Research, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access