Editors:
- the first volume to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies
- Includes supplementary material: sn.pub/extras
Part of the book series: Cancer Drug Discovery and Development (CDD&D)
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Table of contents (25 chapters)
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Front Matter
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General Overview
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Front Matter
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Nitric Oxide and the Pathogenesis of Cancer
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Front Matter
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Dual Roles of Nitric Oxide in Protecting or Inducing Cell Death
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Front Matter
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Role of Nitric Oxide in Metastasis
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Front Matter
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Nitric Oxide as a Sensitizing Agent for Chem-Radio-Immunotherapy
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Front Matter
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About this book
Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important therapeutic applications in several diseases such as inflammatory diseases, erectile dysfunction, inflammation, pain and neural protective activity. However, the role of NO in cancer and its application in therapy has received little attention. This monograph will be the first to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies.
Editors and Affiliations
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Dept. Microbiology, Immunology &, Molecular Genetics, University of California, Los Angeles, Los Angeles, USA
Benjamin Bonavida
Bibliographic Information
Book Title: Nitric Oxide (NO) and Cancer
Book Subtitle: Prognosis, Prevention, and Therapy
Editors: Benjamin Bonavida
Series Title: Cancer Drug Discovery and Development
DOI: https://doi.org/10.1007/978-1-4419-1432-3
Publisher: Humana New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media, LLC 2010
Hardcover ISBN: 978-1-4419-1431-6Published: 17 June 2010
Softcover ISBN: 978-1-4614-2611-0Published: 05 September 2012
eBook ISBN: 978-1-4419-1432-3Published: 16 June 2010
Series ISSN: 2196-9906
Series E-ISSN: 2196-9914
Edition Number: 1
Number of Pages: X, 250
Topics: Cancer Research, Oncology, Pharmacology/Toxicology