Recognition Receptors in Biosensors

1. Front Matter

   Pages i-xvi

   PDF

2. Sensor Surface Chemistry and Receptor Immobilization

   1. Front Matter

      Pages 1-1

      PDF

   2. Principles of Biomolecular Recognition

      • Kalju Kahn, Kevin W. Plaxco

      Pages 3-45

   3. Surface Sensitization Techniques and Recognition Receptors Immobilization on Biosensors and Microarrays

      • Vincent Dugas, Abdelhamid Elaissari, Yves Chevalier

      Pages 47-134

   4. Analytical Tools for Biosensor Surface Chemical Characterization

      • Hans Jörg Mathieu

      Pages 135-173

3. Natural Recognition Receptors

   1. Front Matter

      Pages 176-176

      PDF

   2. Enzyme for Biosensing Applications

      • Béatrice D. Leca-Bouvier, Loïc J. Blum

      Pages 177-220

   3. Antibodies in Biosensing

      • Amber C. Donahue, Maher Albitar

      Pages 221-248

   4. Peptides as Molecular Receptors

      • Ibtisam E. Tothill

      Pages 249-274

   5. Carbohydrates as Recognition Receptors in Biosensing Applications

      • Yann Chevolot, Sébastien Vidal, Emmanuelle Laurenceau, François Morvan, Jean-Jacques Vasseur, Eliane Souteyrand

      Pages 275-341

   6. Nucleic Acid Diagnostic Biosensors

      • Barry Glynn, Louise O’Connor

      Pages 343-363

   7. Tissue-Based Biosensors

      • Victor Acha, Thomas Andrews, Qin Huang, Dhiraj K. Sardar, Peter J. Hornsby

      Pages 365-381

   8. Biosensing with Plants: Plant Receptors for Sensing Environmental Pollution

      • S. K. Basu, I. Kovalchuk

      Pages 383-413

   9. Bacteriophage-Based Biosensors

      • Mohammed Zourob, Steven Ripp

      Pages 415-448

4. Synthetic and Engineered Receptors

   1. Front Matter

      Pages 450-450

      PDF

   2. Antibody Engineering for Biosensor Applications

      • Neal A. E. Hopkins

      Pages 451-529

   3. Genetically Engineered Proteins as Recognition Receptors

      • Jonathan D. Dattelbaum

      Pages 531-563

   4. Biosensing Systems Based on Genetically Engineered Whole Cells

      • Anjali Kumari Struss, Patrizia Pasini, Sylvia Daunert

      Pages 565-598

   5. Photosynthetic Proteins Created by Computational and Biotechnological Approaches in Biosensing Applications

      • Maria Teresa Giardi

      Pages 599-630

   6. Oligonucleotides as Recognition and Catalytic Elements

      • Keith E. Herold, A. Rasooly

      Pages 631-674

Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, “attractive” force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.

• Biomedical Engineering
• Biophysics
• Biosensor
• Biosensors
• Microarray
• Peptide
• Recognition Receptors
• Zourob
• enzymes
• nanotechnology
• photosynthesis
• polymer
• protein
• proteins
• tissue

• GDG Environnement Ltée, Trois-Rivieres, Canada

  Mohammed Zourob

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